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The LCGC Blog

Getting the Best Repeatability from Your Quantitative Gas Chromatography

I'm often asked: “what reproducibility should I expect to get from my [insert instrument manufacturer and model]?” So, most folks are referring to the repeatability aspects of precision, as in: “what relative standard deviation (usually expressed at %RSD) for peak area or quantitative result should I be able to achieve from repeat injections from a single vial of sample?” Read more


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LCGC TV

Combining Space-Based and Time-Based Separations and 3D LC: Is It Practical?

Space-based and time-based separations are often a preferred approach. Peter Schoenmakers from the University of Amsterdam discusses how they can be combined and the benefits of this approach. He also discusses the complexities of 3D LC. Read more


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Featured Article

New Sample Preparation Products and Accessories for 2017

This yearly report on new products introduced at Pittcon 2017 (or in the preceding year) covers sample preparation instrumentation, supplies, and accessories. Read more


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More Featured Articles

New Gas Chromatography Products for 2016–2017

An annual review of new developments in the field of gas chromatography (GC) seen at Pittcon 2017 and other venues in the past year. Read more


Evaluation of Modified QuEChERS for Pesticide Analysis in Cannabis

Well-established techniques used by the food safety industry, such as QuEChERS sample preparation followed by LC–MS/MS for the analysis of multiresidue pesticides, are evaluated for use with cannabis plant material.We evaluated a modified QuEChERS LC-MS/MS method for analysis of multiresidue pesticides. Read more


Liquid Chromatography–Time-of-Flight Mass Spectrometry for Cannabinoid Profiling and Quantitation in Hemp Oil Extracts

The method presented here allows for the accurate, precise, and robust speciation, profiling, and quantification of cannabinoids in hemp oil extracts and commercial cannabinoid products for research and development laboratories. Read more

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New Webcasts

The Application of Spectral Accuracy to Mass Spectrometry for Enhanced Formula ID and Mixture Analysis

Tuesday, June 13, 2017
11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
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Using Magnetic Sector GC–HRMS in a Commercial Dioxin Lab

Wednesday, June 14, 2017
11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
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Who Cares about SVOCs? The Next Generation of Product Emission Testing for Indoor Exposure Modeling

Friday, June 16, 2017
11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
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How to Understand Measurement Uncertainty in TOF Mass Spectrometry and Ion Mobility-Mass Spectrometry

Wednesday, June 21, 2017
11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
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Complete Structural Insight into Therapeutic Proteins: Using Mass Spectrometry Under Native & Denaturing Conditions
Part I: Simplified Mass Spectral Characterization of Complex Biotherapeutic Drugs Under Native and Denaturing Conditions

Wednesday, June 28, 2017
11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
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Complete Structural Insight into Therapeutic Proteins: Using Mass Spectrometry Under Native & Denaturing Conditions
Part II: From Optimized Sample Preparation to Data Analysis: LC-MS Analysis of Therapeutic Proteins on the Intact and Subunit Level

Thursday, July 13, 2017
11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
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On Demand Webcasts

Authenticating Botanicals and Herbal Supplements Using UPLC-QToF-MS and a Metabolomics Approach


Editors' Series: Sample Preparation: The Forgotten Dimension in HPLC

Characterization of Substances in Food Packaging Migration Studies using LC- and GC- coupled to High Resolution Accurate Mass (HRAM) Mass Spectrometry


A Risk-Based Approach to Reviewing Electronic Chromatographic Data and Audit Trails with Data Integrity in Mind

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