The LCGC Blog

State of the Art in Microscale-LC Stationary Phase Formats

In an effort to better understand the current application potential of microscale liquid chromatography (micro-LC), I picked up a few recent review articles from the literature. What one immediately appreciates from glancing through the literature for such information, is that there are a lot of different configurations and alternative formats, which can be placed under the micro-LC umbrella. Learn more

Revolutionary Light Scattering Detector from Tosoh Bioscience
The LenS₃ MALS detector offers the highest sensitivity (2 ng of sample loading for mAbs) and R_g values below 10 nm! Learn more

Featured Articles

2019 Salary Survey: What We Found

The 2019 LCGC salary and employment survey extracted from calendar years 2018–2019 trends shows a slight increase in average salaries over previous years, and a narrowing of the gender gap in several categories. Learn more

News for UHPLC Users
FlexFire is the best column in the 40-year history of Develosil. Designed to deliver supreme durability and maximum flexibility with 1.6, 2.6 and 5 µm particles (porous) for (U)HPLC. With improved endcapping technology and new design of porous silica, FlexFire withstands the harshest conditions and delivers use after use. With a variety of functional groups and particle sizes, FlexFire is designed for scalability and transferability. Learn more

The Importance of Tuning and Calibration in Liquid Chromatography–Mass Spectrometry (LC–MS)

In LC–MS, the importance of tuning and calibrating the mass spectrometer cannot be overemphasized. There are six main aspects to address. Learn more

The Proton OnSite Hydrogen Lab Server produces up to 18.8 SLPM of ultra-high purity hydrogen gas sensing demand and adjusting production accordingly. When installed into a gas system, it can serve numerous floors and rooms with a constant, pure stream of hydrogen gas. This compact generator produces the equivalent of four cylinders of hydrogen every day – eliminating the cost and hazards associated with delivered gas. Learn more

Looking at the Past to Understand the Future: Soxhlet Extraction

To better understand modern sample preparation techniques–such as ultrasound-assisted extraction, microwave-assisted extraction, and pressurized solvent extraction–we should look at the lessons these methods took from Soxhlet extraction. Learn more

Tools and Information for Assured Data Integrity and Regulatory Compliance
FDA and other regulatory bodies have continued to focus on Data Integrity, which has globally elevated the profile of laboratory compliance. Laboratories in many regulated industries must find a way of balancing continued operation of the lab with performing essential gap analysis and lab improvement projects to satisfy compliance and data integrity requirements. Access a series of resources to help you understand the latest regulatory trends and approaches for assured data integrity and laboratory compliance. Learn more