Current Trends in Mass Spectrometry e-newsletter:
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LCGC North America
October 29, 2019
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Presented by LCGC and Spectroscopy

Featured Articles

Ionization Efficiency for Environmentally Relevant Compounds Using Atmospheric Pressure Photoionization Versus Electrospray Ionization

In this study, atmospheric pressure photoionization (APPI) is compared to the default ionization method, electrospray ionization (ESI), for solution-phase samples. These mass spectrometry methods are compared and optimized relative to artificial wastewater for the detection and quantitation of pharmaceuticals frequently found as environmental contaminants.
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New Leak Detector
Redesigned and better than ever, Restek’s electronic leak detector lets you pinpoint small gas leaks quickly and accurately. Now, there’s no more waiting for a full charge—the new unit can be operated during charging or used up to 12 hours between charges. It now comes with a flexible charging kit that includes both a universal AC power adaptor and a USB charging.
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Recent Advances in Hyphenated Chromatography and Mass Spectrometry Techniques and Their Impact on Late-Stage Pharmaceutical Development

In late-stage pharmaceutical development a new generation of high-resolution mass spectrometers and ion mobility mass spectrometers operate as orthogonal separation techniques and have greatly increased the ability to resolve impurities and increase the level of analytical information gained from a single analysis.
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Quantitative Analysis of PFAS in Drinking Water Using Liquid Chromatography Tandem Mass Spectrometry

Per- and polyfluoroalkyl substances (PFAS) are found in firefighting foams and consumer products. They are ubiquitous in the environment and are an emerging human health concern. This work compares the 2009 and 2018 revised US Environmental Protection Agency (EPA) LC–MS/MS methods of analysis for PFAS in drinking water.
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Novel Methods Using Mass Spectrometry for Food Safety—From Contamination to Nutrition

In the human food supply, public confidence is affected by contaminants and misreporting of nutritional information. This article highlights three events that required development of new mass spectrometry methods, including the detection of pesticides (such as fipronil and glyphosate), and the detection and quantification of fat-soluble vitamins.
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Application Notes

Automated Metabolic Stability Assays

Automated metabolic stability assays with sample incubation and LC-MS/MS determination are presented for use in drug metabolism and pharmacokinetic (DMPK) laboratories.
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How Labs Are Coping with the Global Helium Shortage

Note discusses how labs are coping with the worldwide helium shortage.
Download the application note.


NEW WEBCASTS

How to Approach Preparative LC for Compound Purification in the Research and Development Laboratory

Thursday, Nov. 7, 2019 at 11 am EST | 8 am PST | 4 pm GMT | 5 pm CET

Identifying and Quantifying Aspartate and Iso-Aspartate Isomers and Other Difficult PTMs in Proteins

Thursday, Nov. 7, 2019 at 11 am EST | 8 am PST | 4 pm GMT | 5 pm CET

 

Non-targeted Screening for Environmental Water Quality Monitoring

Thursday, Nov. 14, 2019 at 11 am EST | 8 am PST | 4 pm GMT | 5 pm CET

ON DEMAND WEBCASTS

Does Your Electronic Data System Meet 21 CFR Part 11 and CGMP Requirements?

Multi-Detector SEC Characterization of Polymer Architectures

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