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The LCGC Blog: Are we scared to properly explore selectivity options in HPLC?
Much has been written about options for increasing efficiency in HPLC — primarily through the use of core shell and sub-2-µm particles. However, many separations can only be effectively improved by optimising selectivity — resolution is a function of selectivity, efficiency and retention, with selectivity being the most effective at achieving good resolution. |
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| New Agilent AdvanceBio RP-mAb |
The only reversed-phase columns focused on mAb characterization with high resolution and fast analysis. The robust Poroshell packed bed and 2 μm inlet frit extends column lifetime by preventing inlet blockage.  Save 25% on your purchase. |
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Screening Environmental Pollutants in Water Samples
In this new video from LCGC TV, Anthony Gravell of Natural Resources Wales discusses the advantages of GCxGC for the analysis of passive sampling extracts and how GC–MS can be applied to the analysis of passive sampling extracts. |
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LC Troubleshooting: Column Protection: Three Easy Steps
Sometimes it may seem like you are spending most of your laboratory budget buying liquid chromatography (LC) columns, however, with reasonable care, the column should be a small proportion of the total LC analysis costs. |
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| Need GC Troubleshooting Help? |
The CHROMacademy interactive GC Troubleshooter, sponsored by Thermo Scientific, was designed with busy chromatographers in mind. In 3 simple steps ChromAcademy can help you overcome your instrument, separation and quantitation issues. It's completely free — so if you haven't tried our troubleshooter before you're in for a surprise!  Learn more |
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Photo Credit: Thinkstock Images/Getty Images | Trace-Level Quantitation of Tear Gas Lachrymators in Complex Matrices
GCxGC–TOF-MS is used in forensic analysis for the analysis of tear gas lachrymators. The analysis of a lachrymator standard is shown first, followed by the detection of capsaicin and dihydrocapsaicin at trace levels in a complex extract from contaminated clothing. |
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Photo Credit: ANDRZEJ WOJCICKI/Getty Images | Profiling Alzheimer's Disease Biomarkers in Blood Serum
Alzheimer’s Disease (AD) is one of the most common neurodenerative disorders worldwide. In a new study published in the journal Electrophoresis, scientists present a metabolomics approach based on ultrafiltration followed by capillary electrophoresis coupled with mass spectrometry (CE–ESI–MS) for the fingerprinting of polar metabolites in blood serum. |
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