LCGC North America e-Separation Solutions
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LCGC North America | e-Separation Solutions
December 10, 2015
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The LCGC Blog

The LCGC Blog: Why Column Screening is Better than Mobile-Phase Screening for LC–MS Method Development
I now hold to be true: It is much more efficient to screen column chemistries to achieve optimum separations for a set of target analytes, than it is to play with different mobile-phase conditions on a single column.
LCGC TV
LCGC TV: Robert T. Kennedy, Part 4: Analytical Chemists in the Field of Metabolomics
In this video, Robert T. Kennedy of the University of Michigan discusses the challenges of metabolomics – coping with data overload, dealing with small amounts of sample, and improving analysis through derivatization. He also talks about what it's like to be an analytical chemist in a biologist's world, and convincing the “omics” community of the importance of chromatography.
University students and staff get 5 Years of Free Access to CHROMacademy made possible by Agilent Technologies- the world's premiere measurement company.
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Featured Articles

Split-Vent Traps: GC's Dirty Secret
In gas chromatography split injection systems, as much as 99% or more of the injected sample never enters the column: It is released downstream of the inlet where it can encounter and possibly perturb precision gas control devices. The split-vent trap acts to prevent or at least moderate such effects. This article addresses the operation and maintenance of split-vent traps.

Separation Science in Drug Development, Part III: Analytical Development
An overview of modern practices of separation science in small-molecule drug development, focusing on HPLC method development.
Neonicitinoids from Chem Service
Neonicotinoids are a group of systemic agricultural insecticides resembling nicotine in structure. The most widely used is imidacloprid. Recently, use of neonicotinoids has been associated with the decline in the bee population.
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Featured Products
Wyatt Separation of Structural Analogs
The µDAWN™ is the world's first multi-angle light scattering (MALS) detector that can be coupled to any UHPLC system in order to determine absolute molecular weights and sizes of polymers, peptides, and proteins. Learn more YMC-Triart ExRS is stable at pH 1-12, and is mechanically stable at elevated pressure and temperature. It features a high carbon loading (25%) – ideal for the separation of isomers. Learn more
 
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