The LCGC Blog

Attend the Premier Conferences for Capillary and Comprehensive Separations in 2019

From May 12 – 17, 2019 at the Hilton Ft. Worth in Ft. Texas, I will be co-chairing (together with my colleague Prof. Dan Armstrong) the 43rd International Symposium on Capillary Chromatography (ISCC) and the 16th GC×GC Symposium. I am writing to tell you this not only because organizing a meeting is quite an undertaking, but also because I am really excited about how this event is shaping up. Read more

Tosoh Bioscience has published an application note entitled, "U/HPLC Workflow Solution for Biosimilar Characterization". The molecular similarity between Humira® and Yervoy® biosimilars and the corresponding innovator reference products is examined using multiple analytical chromatographic techniques including SEC, RPC and HIC. Learn more: download AN109 at www.tosohbioscience.com.

Featured Articles

Molecular Imprinting for Sample Preparation

Molecularly imprinted polymers can replace conventional sorbent materials in sample preparation techniques such as solid-phase extraction (SPE), solid-phase microextraction (SMPE), and matrix solid-phase dispersion (MoMSPD), offering increased selectivity over the target analytes. Read more

A Guide to Finding the Ideal HPLC Column

• HPLC 101 provides definitions and terminology
• Answers to common questions when starting your column selection process
• "How-To" page helps you choose a product that's right for your application
• Care and Storage section advises on maximizing the life of your product
• Technical References include resin specifications and useful chromatography calculations

Download our Hamilton HPLC Columns Reference Guide today!

What Can Two-Dimensional Liquid Chromatography Offer the Pharmaceutical Industry?

The evolution of two-dimensional liquid chromatography (2D-LC) instruments along with improved software capabilities has transferred 2D-LC from the hands of experienced researchers to functioning analytical laboratories in the pharmaceutical industry. 2D-LC offers chromatographers novel solutions to problems ranging from analyzing complex samples requiring excessively large peak capacities to separating simple compounds that are difficult to resolve. Recent developments in 2D-LC and 2D-LC–MS have demonstrated the potential of this technique in practice and 2D-LC is set to become an essential tool in the pharmaceutical sector to address problems ranging from coelution, peak purity assessment, simultaneous achiral-chiral analysis, genotoxic impurities, and more. Read more

Exclusive Interview from ASMS 2018

Transform Small Molecule Characterization and Identification in Drug Development. Watch the Video