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December 5, 2019
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The LCGC Blog

The Exposome: Is It Too Vast to Tackle?

I run into scientists all the time who have never heard the term exposome. Most are not intimately connected in the analytical world; these days, analytical scientists seemingly expect “ome” and “omics” to be tacked onto pretty much anything. But “omics” is certainly more than a fad, and most in the business can connect with common concepts like proteomics, metabolomics, lipidomics, and genomics. Learn more


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Hamilton HPLC Application Index - Online!
Three easy steps and you have access to almost 1400 compounds that have been separated on Hamilton polymer-based HPLC columns.
• Compounds are listed alphabetically
• Keyword search makes it even easier to get the chromatograms and separation conditions
• Get valuable literature references
Check out Hamilton’s online HPLC Application Index today!


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The Emerald Conference
The Emerald Conference is the most advanced technical and comprehensive science conference in the cannabis industry. It is the leading industryforum for discussion on discovery science, as well as how science and data support best practices in cultivation, production, and qualityassurance. The Emerald Conference has become a must-attend event for scientists in analytical testing, cultivation & extraction science, pre-clinical research and development, and formulations Learn more


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Featured News

LCGC Announces the 2020 Winners of the Lifetime Achievement and Emerging Leader in Chromatography Awards

LCGC, the leading resource for separation scientists, is proud to announce that Daniel W. Armstrong and Szabolcs Fekete are the winners of the 13th annual LCGC Lifetime Achievement and Emerging Leader in Chromatography Awards, respectively. Learn more


Featured Articles

Data Integrity Focus, Part IX: Understanding Data Integrity Metrics for Chromatography

Here, we review the regulatory expectations of metrics for monitoring data integrity and discuss their practical implementation in a regulated chromatography laboratory. Learn more


Ionization Efficiency for Environmentally Relevant Compounds Using Atmospheric Pressure Photoionization Versus Electrospray Ionization

In this study, atmospheric pressure photoionization (APPI) is compared to the default ionization method, electrospray ionization (ESI), for solution-phase samples. These mass spectrometry methods are compared and optimized relative to artificial wastewater for the detection and quantitation of pharmaceuticals frequently found as environmental contaminants. Learn more


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Sampling: The Ghost in Front of the Laboratory Door

How does one meet the most demanding part of an analysis—sampling? A typical example is soil, which presents a twofold problem for the analyst: first, the selection of the sites where the samples are taken, and second, the reduction of a sample (for example, 1 kg) to the analysis aliquot size (for example, 10 μL). This paper describes the details of sampling issues. Learn more

The Road to a Successful Contract Research Organization (CRO) Relationship

Incognito navigates the potentially precarious path to a successful relationship with a contract research organization (CRO). Learn more



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NEW Sample automation & concentration platform

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APPLICATION NOTE

Multi-Attribute Analysis of Monoclonal Antibodies

Multi-attribute analysis combines protein A affinity chromatography, SEC, and LC/MS in a 3D setup for assessment of features including mAb titer and size variants. / Read more /


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Data Management and Integrity Expectations from the World Health Organization and PIC/S

Tuesday, Dec. 10, 2019 at 10 am EST | 9 am CST | 3 pm GMT | 4 pm CET
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Thorough and Reproducible Analytical Characterization of Innovator and Biosimilar Pair

Europe Broadcast: Wednesday, Dec. 11, 2019, at 2 pm GMT | 3 pm CET
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The CHROMacademy Essential Guide Webcast: Understanding GC Sample Introduction

Thursday Dec. 12, 2019, 11:00 am EST | 8:00 am PST | 4:00 pm GMT | 5:00 pm CET
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Editors’ Series: Streamlined Characterization of Antibody–Drug Conjugates by Two-Dimensional (2D) and Four Dimensional (4D) LC/MS

Thursday, Dec.12, 2019 at 11 am EST | 8 am PST | 4 pm GMT | 5 pm CET
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Capillary Flow LC–MS Using Micro Pillar Array Columns: Combining Nano Flow Sensitivity with Analytical Flow Robustness and Throughput

Friday, Dec. 13, 2019 at 10 am EST | 9 am CST | 3pm GMT | 4 pm CET
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