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October 2010
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Technology Forum

Gas Chromatography
World events such as the Gulf Oil Spill only serve to remind us how important the techniques of GC and GC-MS are. With testing of the food chain largely accomplished with these techniques, GC and GC-MS are once again in the spotlight. Joining us for this discussion on gas chromatography this month are Eric Phillips of Thermo Fisher Scientific and Ngoc Nguyen of Phenomenex.
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New XSelect Prep Columns. New Chemistries. Higher loading.
The new Charged Surface Hybrid (CSH) prep columns offer the greatest benefits to purification scientists including fast screening using ACQUITY UPLC CSH columns that can be directly scaled to XSelect Prep Columns. These preparative columns, offered in Optimum Bed Density Technology (OBD), will provide:

• high loadability of bases using simple low or high pH mobile phases
• long, predictable column lifetimes
• widest selectivity range in CSH C18, CSH Fluoro-Phenyl, CSH Phenyl-Hexyl stationary phases Find out more


 

Featured Articles

Key Challenges Facing Environmental Analysis
Environmental testing incorporates a diverse range of applications from emissions and bioaccumulation to chemical exposure and human health.
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Chromatography on the Front Lines of the Gulf Oil Spill
The tragic Gulf Oil Spill, which has gripped the nation's collective consciousness for most of the summer, is only now beginning to turn the corner toward a long, slow recovery.
More...
 

Unrivalled Cleanliness:

With highly sensitive chromatography applicationsrequiring complete elimination of any potentially contaminating substances, it is vitally important that you can be sure that all equipment used is clean, with a high level of purity. National Scientific Mass Spec Vials are pre-cleaned and tested as standard to provide you with an extra level of assurance.

To get your free sample pack, visit www.nationalscientific.com/mscertified now!

Featured Application Note

Effect of Temperature on Elution Order in GC

When analyzing via GC, the desired separation can sometimes be achieved by changing the oven program. This technique takes two properties into account: a compound’s boiling point and its ability to interact with the stationary phase.
Read more...

 
 

Featured Webcasts & Podcasts

Increase LC–MS Throughput and Improve ROI for Biological Samples— Tuesday, October 26, 2010 at 11:00 AM EST, 8:00 AM PST
We will present a case study based on this strategy as a tool to analyze 45 drugs of abuse in performance horses.
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LC and LC–MS in the Pharmaceutical Industry: Metabolite Analysis — Wednesday, November 3, 2010, 8:00 AM PT; 11:00 AM ET; 4:00 PM GMT
Dr. Kevin A. Schug, Assistant Professor at the University of Texas at Arlington will discuss fundamental and applied studies of LC and LC-MS for trace quantitative analysis of small molecules and metabolites
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Developing Better Methods for Reversed Phase HPLC (Part 2)— On Demand
The Essential Guide from LCGC’s CHROMacademy presents Part 2 of our series on Developing Better Methods for reversed Phase HPLC.
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Molecular Imaging for Localization and Distribution of Proteins, Peptides, Drugs and Metabolites by Mass Spectrometry— On Demand
This presentation will detail the use of both MALDI-TOF and FTMS Mass Spectrometers to measure the tissue distribution of a variety of proteins, peptides, lipids, or small molecule drugs and metabolites in various tissues
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Supercritical Fluid Chromatography in Theory and Practice
In this podcast series, we’ll be discussing how users can benefit from supercritical fluid chromatography (SFC) in their laboratories.
More...
 

Optimizing Chromatographic Conditions for Protein Analysis with the ACQUITY UPLC H-Class Bio System
Biopharmaceutical proteins are large, complicated molecules and demand multiple modes of analysis to ensure complete characterization of the sample.
More...

Featured Products


No Matter What Your Purification Scale, Waters has Your Solution.
Waters is the laboratory technology leader that first brought mass-directed purification to the commercial market, and Waters is once again first to bring a single-vendor solution that encompasses the entire purification range. From HPLC to the newest SFC innovations, to world-class service and worldwide support, you can depend on Waters for all of your purification needs. waters.com/prep

 

Ultra Fast, Ultra Sensitive GCMS
Ideally suited for Fast GC or comprehensive GC/MS (GCxGCMSq) analyses, Shimadzu's GCMS-QP2010 Ultra features best-in-class scan speed and sensitivity with a maximum scan speed of 20,000 u/sec and a 500:1 S/N ratio in EI mode. The optional twin-line MS system eliminates the need to swap columns while an "Ecology mode" significantly reduces operating costs. www.ssi.shimadzu.com/GCMSAL

   
     
CHROMmunity
A service by LCGC and CHROMacademy
Forum and Networking site for Chromatographers.

Forums:


  • What if a compound has 2 pKa's?
  •  
  • Using RP-HPLC to calculate Log D
  •  
  • The Best HPLC
  •    
    Blogs:
  • Kevin Schug looks at the worrisome trend of younger students losing interest in science.
  •    

    Join in the Big Chromatography Conversation.     Free Registration.»

    Market Profile

    The Analytical and Life Science Instruments Industry
    The last few years have been particularly eventful for instrument companies as the prior prospects were hampered by the global recession, which affected some of the analytical and life science instrument sectors more than the others. More...


    Ask LCGC

    Extending HPLC Column Life

    Q: Can you suggest possible causes of this problem? How long should it be degassed under vacuum?
       
    A: I don’t have sufficient information to answer the question exactly, but I can give you some estimates.
     
    Click here to submit your questions LCGC answers your technical questions each month. Please submit your questions here. We look forward to hearing from you.
     
     


     
    Upcoming Events

    20–24 September 2010
    MipTec Expo
    Basel, Switzerland.
    » Visit the website

    21–24 September 2010
    ILMAC
    Basel, Switzerland.
    » Visit the website

    28 September–1 October 2010 HET Instrument Amsterdam, Netherlands.
    » Visit the website

    5–6 October 2010
    Conference– Automation in the Chromatography Laboratory
    Hertfordshire, UK.
    » Visit the website

    5–7 October 2010
    CPhI Worldwide
    Paris, France.
    » Visit the website

    19–22 October 2010
    SOFT- Society of Forensic
    Toxicologists
    Richmond, VA.
    » Visit the website

    27–30 October 2010
    45th ACS Midwest Regional
    Meeting
    Wichita, KS.
    » Visit the website

    7–10 November 2010
    3rd International Conference on Polyolefin Characterization
    Shanghai, China.
    » Visit the website

     

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