The LCGC Blog
In my previous blog, I discussed the possibility of backflash in splitless GC injection and its effect on quantitative reproducibility and carry-over. While much is written in the literature on optimization of splitless injection conditions, little is available on the implementation and optimization of increased head pressure (pressure pulsed) injection, so we will concentrate on this aspect of injection optimization. Read more
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The molecular complexity of monoclonal antibodies (mAbs) makes accurate characterization challenging. This ebook highlights versatile and automated mass spectrometry-based approaches for intact protein analysis, peptide mapping, and glycan analysis that deliver quick and reliable answers.  Download the eBook
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Featured Articles
By understanding the relationship between various parameters and ionization efficiency, analysts can realize the full potential of the LC–MS technique. Read more
A laboratory relocation yielded insights as to how to deliver gases that are up to the requirements of the separations at hand, within a safe working atmosphere. Read more
In the first of a three part series, we focus on the method as a whole and considerations for avoiding ambiguities and inconsistencies between laboratories. Read more
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An important advantage of standardized methods is that they enable comparability between laboratories and across studies. In this work, the author used a standardized targeted kit to demonstrate the accuracy, sensitivity, and reproducibility of the approach, analyzing serum samples obtained from type 2 diabetes study subjects and healthy controls.
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Featured News
Shimadzu has been awarded the 2018 NRW.Invest Award by the North Rhine Westphalia (NRW) region of Germany. Read more
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Application Note
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This application note demonstrates a robust and reliable method to identify and quantify phthalates with the Agilent Intuvo 9000 GC coupled with an MS-HES.
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PharmaFluidics' game-changing chip-based chromatography column for nano-LC, lets you detect more molecules in tiny, complex biological samples: excellent separation, unprecedented robustness and reproducibility, perfect for lipidomic, metabolomic and peptide profiling.  / Learn more / |
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