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LCGC North America
October 5, 2017
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LCGC TV

Three-Dimensional vs Two-Dimensional LC: Peak Capacities and Orthogonality in 3D LC

Peter Schoenmakers from the University of Amsterdam discusses what he found when he compared the potential peak capacities of two and three-dimensional LC. He also reviews how he approaches orthogonality in a 3D LC separation. Read more


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Fast, Reproducible Pesticide Residue Analysis in Food

Traditional techniques used to perform the extraction of pesticides from food matrices are time consuming, solvent intensive and can deliver inconsistent results. The need for economical, fast, reproducible testing protocols exists. Perform consistent extraction of pesticides for analytical quantitation in 10 minutes. The PLE can dramatically improve reproduciblity of results, speed and cost of extractions. Learn more


The LCGC Blog

Potential for use of Stable Isotope–Labeled Internal Standards in Gas Chromatography–Vacuum Ultraviolet Spectroscopy Methods

Internal standards (IS) are commonly incorporated into quantitative methods to increase accuracy and precision. An IS is a compound that is different than the analyte of interest, has similar physicochemical properties to the analyte, and is added to samples, calibration standards, and quality control samples in a known quantity. It should not be present in the sample, it should be available in high purity, and it should be easily differentiable from the analyte of interest. Read more


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HILIC Lipidomics Columns

View the growing list of zwitterionic, HILIC column applications from The Nest Group™. The list describes separations of lipids and phospholipids by head group. Included literature references provide an overview of the capabilities of these silica and polymer based HILIC chemistries. Try iHILIC® Fusion columns or SPE cartridges today! The Nest Group, Inc. - “Not Just Columns ... Answers!”

Featured Articles

Identifying Post-Translational Modifications in Monoclonal Antibodies

Analyzing post-translational modifications—such as glycosylation, oxidation, and deamidation—at different levels can reveal different types of information. Read more


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Who is Sciencix?

Sciencix has been a trusted provider of top brand HPLC instrumentation products for over 30 years. Our products are equivalent to OEM products and can help reduce repair expenses by 15% to 30%. Our mission is to serve our customers by delivering quality service and quality products at a reasonable price while exceeding expectations, every moment. Please visit us at www.sciencix.com.


How to Take Maximum Advantage of Column-Type Selectivity

When developing or modifying an LC separation, a common strategy is to change selectivity by choosing a new column. Here's guidance for making that selection. Read more


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Take this short survey on flow splitting applications in LC-MS and HPLC!

Please share your thoughts on flow splitting applications in LC-MS and HPLC in this simple market research survey that will only take a few minutes to complete. CLICK HERE

Featured Articles, Continued

Quantification of Polybrominated Diphenyl Ethers in Avian Dried Blood Spots by Gas Chromatography–Tandem Mass Spectrometry Coupled with Simple Sample Preparation

With a simple liquid extraction approach and a short, 13-min GC method, dried blood spots can be analyzed effectively and rapidly. This method demonstrates that dried blood spot cards are an effective technique for toxicological studies. Read more


Featured News

Chinese American Chromatography Association Invites Awards Nominations

The Chinese American Chromatography Association (CACA) invites nominations for three awards: the 2018 CACA Young Investigator Award; the 2018 CACA Student Excellence Award; and the HPLC 2018 Student Travel Award. Read more


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From reviewing FDA and ICH guidance to analyzing the latest regulatory policies, IVT's annual Stability Testing summit is the flagship event for stability professionals to convene in order to develop and hone your organization's stability testing procedures. Gain insight on the latest updates and challenges including off-label storage, change management, lean stability processes, comparability studies, risk analysis, stability chamber excursions, forced degradation and much more! Learn more

Application Notes

Fast LC/CMS Screening for EDTA in Blood

High-profile murder cases have forced forensic labs to improve detection of EDTA in blood. Learn how LC and a single-quad compact mass spectrometer can quickly. read more


Identifying mAb Mutation Sites Using 2D-LC–MS

The Agilent 1290 Infinity II 2D-LC solution with an Agilent 6530 Accurate Mass Quadrupole Time-of-Flight LC–MS was used to determine critical differences between an. read more


Shodex VT-50 2D Column for Glyphosate Analysis

The Shodex VT-50 2D column was used successfully to analyze the non-selective herbicide glyphosate and related adverse compounds using LC-MS under several conditions without tedious extractions (QuPPe) or sample derivatization. read more

FEATURED PRODUCTS

ViscoStar III - On-line Viscometry

The ViscoStar III's sensitivity, dynamic range, resolution and stability surpass other GPC viscometers by at least an order of magnitude—all while retaining robustness, ease-of-use and serviceability. Learn more

Sugar/Carbohydrate Analysis

The ALEXYS Carbohydrates Analyzer based on (U)HPLC with Pulsed Amperometric Detection and its dedicated flow cells assures for stable and sensitive analysis of carbohydrates, mono-, di- and polysaccharides, including lactose free products. Learn more

Quadrex 007-624 GC columns

Quadrex 007-624 GC columns are a low to mid-polarity cyanopropylphenyl dimethylpolysiloxane GC capillary column, equivalent to the USP G43 phase type. 007-624 columns are specifically designed for volatile organic compounds and residual solvent applications. Learn more

SEC/MS Compatible UHPLC Column

The TSKgel UP-SW3000, 2 µm SEC column provides accurate mass determination using non-denaturing SEC/MS. Additionally, the column shows no signs of particle shedding or sample carryover. Learn more

NM Plus Hydrogen Generator

The NM Plus Series features a unique no-maintenance purification system, resulting in ultra high purity carrier grade gas. Software control and safety alarm maximize the benefits and minimize safety concerns. Learn more

New Webcasts

Editors' Series: Modern Liquid Chromatographic Approaches for Successful Characterization of mAbs and Related Products

Tuesday, October 24, 2017 | 11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
Register>>

 

High-Throughput Aroma Analysis of Food Products Using Direct MS

Wednesday, October 25, 2017 | 2 pm EDT | 1 pm CDT | 11 am PDT
Register>>


On Demand Webcasts

Maximizing Return for Routine Environmental Analysis Part 1: Updating Outdated SVOC Instrumentation


Maximizing Return for Routine Environmental Analysis Part 2: Overcoming Common Challenges in VOC Analysis with Updated Technology


Webinar 3: Making Good Methods Even Better

 

Real-Time, Comprehensive Ambient and Fenceline Monitoring Using Direct MS


Balancing Technical Controls, Tools, Transparency, and Trust for a Culture of Data Integrity


Managing Experiments and Projects Beyond Spreadsheets

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