The LCGC Blog
The improved performance of chromatographic detectors, most notably mass spectrometers, has enabled many advances in analytical science, however, one such advance may be given less prominence than perhaps it should. Learn more
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News for UHPLC Users
FlexFire is the best column in the 40-year history of Develosil. Designed to deliver supreme durability and maximum flexibility with 1.6, 2.6 and 5 µm particles (porous) for (U)HPLC. With improved endcapping technology and new design of porous silica, FlexFire withstands the harshest conditions and delivers use after use. With a variety of functional groups and particle sizes, FlexFire is designed for scalability and transferability.
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Featured Articles
The high levels of non-volatile salts typically used in ion-exchange separations are incompatible with mass spectrometry. But the desire to directly couple these two powerful techniques has prompted researchers find solutions to this problem. Here are three approaches.
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Hamilton HPLC Application Index - Online!
Three easy steps and you have access to almost 1400 compounds that have been separated on Hamilton polymer-based HPLC columns.
•Compounds are listed alphabetically
•Keyword search makes it even easier to get the chromatograms and separation conditions
•Get valuable literature references
 Check out Hamilton's online HPLC Application Index today!
This integrated analytical approach combines HPLC–MS/MS and GC–MS/MS to detect 36 PFAS migrating into food simulants from packaging.
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New Leak Detector
Redesigned and better than ever, Restek's electronic leak detector lets you pinpoint small gas leaks quickly and accurately. Now, there's no more waiting for a full charge–the new unit can be operated during charging or used up to 12 hours between charges. It now comes with a flexible charging kit that includes both a universal AC power adaptor and a USB charging.  Learn more
HILIC has rapidly evolved into a practical technique. For analyzing highly polar compounds, HILIC can be far more straightforward than GC or reversed-phase LC with derivatization, and can lead to a simpler final method with robustness comparable to that of reversed-phase LC.
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More Featured Articles
The field of sample preparation is undergoing revolutionary change, largely governed by the need for miniaturization while maintaining high selectivity and high analyte enrichment. How up-to-date are you in the advances of sample preparation for chromatographic analysis?
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BIOCHROMATOGRAPHY TRAINING
Developed with the Research Institute for Chromatography–
Sponsored by Agilent—
 Access Free Biochromatography Learning Modules
The impact of ionic strength, buffer capacity, and pH-response on the retention behavior and peak shape of mAb species characterization is evaluated for IEX-MS. The aim of the present study was to understand the impact of ionic strength, buffer capacity, and pH-response on the retention behavior and peak shape of mAb species.
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As a trusted partner in the pharmaceutical industry, Shimadzu provides a variety of instruments and suitable workflows for drug impurity analysis to help ensure compliance to these guidelines.  / Learn more / |
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FEATURED PRODUCTS
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The highest performance LC/TQ available with Agilent's third generation iFunnel design, ideally suited for peptide quant as well as multiresidue applications that require ppt sensitivity. The combination of utmost sensitivity, extended mass range, ease of maintenance with VacShield technology, and the power and flexibility of MassHunter makes this the system of choice for demanding applications.  / Click here for further information / |
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Incorporating core-shell technology, Shimadzu's Velox columns achieve increased separations and faster analysis times on any LC platform, while providing excellent lifetime for the most challenging sample matrices.  / Learn more / |
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Low extractable borosilicate glass sample vials (meets USP Type I and ASTM E438, guidelines) designed for chromatography, with caps and liners to suit your specific application. Don't miss out on quality vials at the best prices – ask your DWK Life Sciences representative.  / Learn more / |
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High Speed Benchtop Centrifuge with a specially designed rotor and 8 adapters and cushions for approved glass MRQ™ (1.2ml) and Max Recovery (1.8ml) single piece, heavy wall autosampler vials. Ideal when plastic vials are not recommended. / Learn more / |
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Kromasil presents the new fully wettable C18 HPLC phase specifically engineered for bioseparations and API manufacturing. Kromasil C18(w) can be loaded and run under 100% aqueous conditions keeping excellent efficiency.
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EXP2 10-32 Adapters allow users to connect 1/32" tubing directly to all 10-32 ports designed for 1/16" tubing. Cost-efficient solution, replaceable components and rated hand-tight to 20,000+ psi (1,400+ bar).
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Cubis® II from Sartorius is a completely configurable, high performance portfolio of balance hardware and software that will align with your unique demands and compliance requirements to maximize operational efficiency and experimental outcomes.
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Quadrex's 007-624 GC capillary columns are specifically configured for the analysis of residual solvents in pharmaceuticals and VOCs. The 007-624 columns are equal to the USP G43 designation and are available in all commonly required 624 configurations.
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As an extension to the VICI Jour® Back Pressure Regulators the new JR-BPR3 offers an extended application range. Pressures from 90-300bar (1300-4200psi) are easily manual adjustable.
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YMC-Triart is offered in 8 distinct stationary phase chemistries – in stainless steel or PEEK-lined columns. Scalable from UHPLC to Prep Scale. Hybrid particles produce robust chemical, physical, and thermal durability. Wide pH range.
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