The LCGC Blog

Using Hydrogen Carrier Gas with Mass Spectrometric Detection

Our recent discussion on the use of hydrogen as a carrier for gas chromatography applications elicited many questions and comments, however one common question was "What are the considerations for using hydrogen carrier with MS detectors? Learn more

Durability and Flexibility
FlexFire, Develosil's newest UHPLC column series, is designed to deliver supreme durability and maximum flexibility. By applying 40 years of manufacturing expertise, Develosil has engineered premium grade porous silica in uniformity, high density, and purity. With improved endcapping technology, FlexFire withstands the harshest conditions and delivers use after use. With a variety of functional groups and particle sizes, FlexFire is designed for scalability and transferability. Learn more

Featured Articles

Mobile Phase Buffers in LC: Effect of Buffer Preparation Method on Retention Repeatability

Many analysts have strongly held beliefs about buffer preparation methods, but these positions are not always supported by experimental evidence. Learn more

Laser Thermal Desorption and GC×GC for Harsh Environment and Planetary Mass Spectrometry

The development of analytical instrumentation for harsh terrestrial environments and outer planet space exploration exponentially increases instrument requirements—for features such as robustness, autonomous operation, and speed—and poses unique system integration challenges. Here, we explore the use of laser thermal desorption coupled to comprehensive two-dimensional gas chromatography (LTD-GC×GC) for use with a compact, high-resolution mass spectrometer for challenging applications. Learn more

Chromatography Fundamentals, Part VII: Influence of Peak Broadening on Detection Sensitivity, Solute Dilution, and Efficiency of Coupled Columns

With these equations, you can predict how solute dilution will affect sensitivity. Learn more