The LCGC Blog

Multipath Liquid Chromatography–Mass Spectrometry: A Veritable Pandora's Box

For several years, our group has been working on a concept that we have termed multipath liquid chromatography. The main idea is to target multiple classes of compounds following a single injection of a sample, the components of which are segregated on-line and directed to separate appropriate paths for simultaneous separation; the streams are then recombined for detection. Read more

Mixed-bed SEC Column

The TSKgel GMPWXL size exclusion chromatography (SEC) column is comprised of particles of various pore sizes from 10 to 100 nm. The mixed bed produces an extended linear calibration range making the column suitable for samples with a broad molar weight distribution (5 kDa to >30,000 kDa). This unique characteristic makes the column ideal for the analysis of viruses, virus like particles, and vaccines. Find out more at www.tosohbioscience.com

Featured Articles

GC Column Maintenance: Tips for Extending GC Column Life

To extend the life of your GC columns, follow these best practices. Read more

The 7th Edition of the International Conference on Polyolefin Characterization (ICPC) will be celebrated in Houston, TX (USA) on October 22-24, 2018. The technical program includes oral and poster presentation covering topics such as, molar mass distribution, comonomer incorporation and distribution, long-chain branching, crystallinity, and rheological properties. A Short Course on Polyolefin Characterization Techniques is scheduled a day before the Conference at the same venue. Learn more

Antibody–Drug Conjugates: Perspectives and Characterization

Comprehensive characterization of ADCs requires increasingly powerful approaches consisting of small- and large-molecule techniques. Read more

Bioinert Versus Biocompatible: The Benefits of Different Column Materials in Liquid Chromatography Separations

In this study, we compare the performance of plastic and metal materials in UHPLC columns designed for the analysis of biological molecules. We evaluate the performance of these materials in terms of inertness, column chromatographic performance, and reproducibility. Read more