The LCGC Blog

Optimizing Sensitivity in Splitless Capillary GC with FID Detection

It is often possible to achieve better sensitivity and lower limits of detection and quantitation using standard gas chromatography (GC) equipment—here I'm referring to a standard split/splitless injection port and a Flame Ionization Detector (FID). Paying attention to some of the fundamental variables as well as some of the more esoteric considerations can lead to much improved method performance. Read more

CE in the Biotechnology & Pharmaceutical Industries: 20^th Symposium on the Practical Applications for the Analysis of Proteins, Nucleotides & Small Molecules

September 9-12, 2018, Hilton San Francisco Union Square, San Francisco, CA.
Join CASSS for CE in the Biotechnology and Pharmaceutical Industries: 20th Symposium on the Practical Applications for the Analysis of Proteins, Nucleotides and Small Molecules on September 9-12, 2018 in San Francisco, CA. This Symposium provides an interactive forum for the discussion of recent development and practical applications of capillary electrophoresis (CE) in the analysis of pharmaceutical and biopharmaceutical industries, including regulatory considerations. Learn more and register now!

15^th Symposium on the Practical Applications of Mass Spectrometry in the Biotechnology Industry

September 9-12, 2018, Hilton San Francisco Union Square, San Francisco, CA
Join CASSS for the 15th Symposium on the Practical Applications of Mass Spectrometry in the Biotechnology Industry on September 9-12, 2018 in San Francisco, CA. The focus of this Symposium is the application of mass spectrometry (MS) for product characterization, process monitoring, formulation development and release testing in the pharmaceutical industry. Learn more and register now!

Featured Articles

The Promise of Metal–Organic Frameworks for Use in Liquid Chromatography

What can metal–organic frameworks offer for liquid chromatography? Read more

Make QuEChERS Even Easier

New Q-sep extraction salts from Restek make an easy technique even simpler. Our new, improved design provides the salts in a more granular form, so they flow freely and are easier to pour than powders. The convenient slim packets are easy to open and fit perfectly into extraction tubes, ensuring complete transfer without any spills. Learn more

Current and Future Chromatographic Columns: Is One Column Enough to Rule Them All?

The packed particle bed format still rules LC columns, but advances continue in monoliths. Meanwhile, newer formats are on the horizon, including microfabricated columns and 3D printed columns. This article provides a critical review of all these technologies and demonstrates how further development of chromatographic columns will be of paramount importance in the future. Read more

PhosphoPeptide & Glycan Desalting

BioPureSPN™ Graphite SPE utilize an activated charcoal bed to both desalt and remove particles. Try BioPureSPN spin columns today for reproducible, high capacity desalting. Now in 96-Well, hybrid weight formats! Tested and proven by leading proteomic laboratories around the world. The Nest Group, Inc. - "Not Just Columns … Answers!" Learn more

Agilent Announces Genohm Acquisition

Agilent Technologies has announced an agreement to acquire Genohm, a developer of highly differentiated, on-premise, and cloud-based software solutions for laboratory management. Read more

AOAC INTERNATIONAL is a globally recognized, 501(c)(3), independent, third party, not-for-profit association and voluntary consensus standards developing organization founded in 1884. AOAC meets annually and offers scientific sessions, workshops, poster presentations, and an Exhibit Hall to meet a variety of analytical needs. The 132^nd AOAC Annual Meeting will take place in Toronto, Ontario, Canada from August 26-29, 2018. For more information, Click Here.