The LCGC Blog
If given the need to determine drug A or its metabolite in blood, 99% of the time I would choose to start with liquid chromatography–mass spectrometry (LC–MS). Read more
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Capcell Core Adamantylethyl (ADME) columns provide a very high hydrophobicity and surface polarity. This unusual basket-shaped structure is considerably different than conventional C18 phases and is especially useful in separating metabolites. Also available in an inert format. Learn more
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Featured Articles
With autosamplers, we need to be extra careful to avoid contamination. Read more
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lnfinityLab Poroshell 120 columns provide exceptional efficiency and reliability, significantly boosting performance from all instruments, whether you want improved HPLC performance, UHPLC performance at lower pressures or the highest UHPLC performance. Three particle diameters- 1.9 µm, 2.7 µm, and 4 µm - allow you to choose the size that best fits your separation needs and is most compatible with your LC systems. Learn more at www.netascientific.com
Here, we see how 2D-LC can solve coelution problems that are difficult or impossible to address using peak purity tools or curve resolution methods.
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The Dioxin Symposium and International PCB Workshop are recognized as the leading international POPs meetings for scientists and regulators. This year, apart from the International PCB Workshop, the Dioxin Symposium will also host the Pre-Dioxin Students Session "All POPs & Pseudo-POPs", five major Special Sessions, and other traditional sessions throughout the meeting. Learn more
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Liquid chromatography (LC) is proving to be a valuable complementary technique to gas chromatography (GC) in cannabis testing for the analysis of cannabinoids, mycotoxins, and pesticides. Read more
Thermal effects in UHPLC and low-density SFC cause peak broadening and distortion. A solution to this problem is to thermally insulate the chromatographic column. Vacuum-jacketed column technology has been developed as a new approach to insulate the column in a practical way. Read more
Featured News
Researchers from Merck and Agilent Technologies have developed a simple and fast generic gas chromatography–flame ionization detection (GC–FID) method for the quantitation of volatile amines in pharmaceutical drugs and synthetic intermediates. Read more
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Application Note
This application note demonstrates a robust and reliable method to identify and quantify phthalates with the Agilent Intuvo 9000 GC coupled with an MS-HES.
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