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June 21, 2012 Follow us on:
Chromatography Corner Challenging Beliefs About How Core–Shell Particles Work In a new paper to be published in the July issue of LCGC North America, Fabrice Gritti and Georges Guiochon of the Department of Chemistry at the University of Tennessee (Knoxville, Tennessee) present results from their latest studies in their research on the kinetic mechanisms of chromatography columns packed with core–shell particles. More...   Kromasil HILIC-D Kromasil HILIC-D is designed for the best selectivity of polar compounds like organic acids, nucleobases, and water soluble vitamins. You may expect the opposite elution order and a different selectivity compared to a standard C18 in reversed phase mode. The phase is low bleed and solvents used when running in HILIC mode are fully compatible for MS detection. For more info and a special offer visit www.kromasil.com/hilic.   New Podcast Series: The 2012 FACSS-SciX Awards Tracking Molecular Transport in Chromatographic Particles with Single-Molecule Fluorescence Imaging Justin Cooper and Joel Harris at the University of Utah are using single-molecule fluorescence imaging to study the dynamics of molecular transport within chromatographic stationary phases. Here is what they have found. More...   New LC Purification solution How much can you purify with a lab-scale LC system? Mining and enrichment in discovery are demanding tasks. Isolating product-related impurities or developing efficient purification processes can also be very laborious. Our new lab-scale gradient-capable purification solution ContiChrom™ can ease the pain. It supports up-scaling from batch to continuous LC, allowing 50% higher yields and purity and up to 10 times more throughput. Learn more.   Featured News ChromaDex and the Scripps Research Institute Collaborate ChromaDex Corporation (CDXC) (Irvine, California, USA) has announced that it has collaborated with the Scripps Center for Metabolomics (La Jolla, California) to generate tandem mass spectrometry data for compounds from the ChromaDex natural products and phytochemical catalog. More...   All the Right Tools—All in One Box Restek’s USLC™ column set represents an incredible range of selectivity with just 4 stationary phases—and the new USLC™ toolbox contains all 4 phases in 1 convenient package! This must-have companion for method developers also includes a guide to help ensure you always choose the right column the first time. www.restek.com/uslc.   FSA Ends Animal Testing in Shellfish Program The Food Standards Agency (FSA) (London, UK) has announced that it has ended the practice of using mice for the detection of paralytic shellfish poisoning (PSP) and lipophilic toxins in commercially harvested shellfish. More...   VICI's New Catalog VICI Valco Instruments Co Inc introduces its new general catalog #65. The VICI catalog has been called “the bible of chromatography”. Its first catalog since 2009, the VICI family presents the latest product developments as well as the full line of Valco and Cheminert® GC, LC, HPLC, and UHPLC valves, fittings, and accessories, as well as Metronics calibration devices and Precision Sampling products. There is even a glossary and handy reference section. Ask for yours today   KineMed and CHDI Collaboration KineMed Inc., (Emeryville, California) and CHDI Foundation (New York, New York) have entered into a collaboration that will see KineMed's isotopic labeling and dynamic proteomics platform be used to investigate the turnover rates of huntingtin protein. More...   Thermo Scientific is now sponsoring CHROMacademy’s HPLC Troubleshooter. Choose from over 50 instrument and chromatographic problems!. Read more.   Featured Products EASY-Spray columns bring even more ease-of-use to performance The unique Thermo Scientific EASY-Spray* design provides uncompromised performance and ease of use in nano LC-MS. The highest quality chromatographic media and device components ensure high precision and robustness for routine operation. Read more.   Multi-Angle Light Scattering Detector Based on Wyatt Technology’s family of multi-angle light scattering detectors, the new DAWN HELEOS-II has 18-angles of detection for the greatest sensitivity for absolute molecular weight and size determinations of polymers and biopolymers in solution. It may be connected in series to any chromatographic system in order to determine absolute molar masses without the use of reference standards or column calibration. Read more.   Recent discussions on CHROMmunity, a Forum and Networking Site for Chromatographers   LC-ESI-MS of Methane Sulfonamide Join in the conversation. Free Registration.>>   Upcoming Webcasts The CHROMacademy Guide To Troubleshooting GC Separations Thursday, June 14, 2012 11:00 AM EDT; 16:00 GMT The Essential Guide from LCGCs CHROMacademy presents the third in our series of webcasts on Practical GC Troubleshooting. In this session, Dr. John Hinshaw (Senior Scientist , BPL Global Ltd) and Tony Taylor (Technical Director, Crawford Scientific), present practical troubleshooting tips for GC separations, with special emphasis on retention time variability, loss of efficiency and poor peak shape. More...   Mass Spectrometry Tool Box - Biopharmaceutical Characterization Wednesday, June 20, 2012 11:00A AM EDT To achieve a greater understanding of your biotherapeutic product and to satisfy the stringent requirements of the regulators, characterization strategies need to be employed throughout biopharmaceutical discovery, development, regulatory approval and production. Mass spectrometric tools can help provide you with the necessary characterization knowledge quickly and confidently. More...   EDITORS' SERIES: A Roadmap for Rapid HPLC Method Development: A Practical Three-Pronged Approach Tuesday, June 26, 2012 11:00 AM EDT HPLC method development is a challenging task, requiring the ability to optimize a large number of dependent and independent variables for complex samples. The traditional method development approach, while well accepted, is difficult to implement in practice, particularly for those with little experience. In this seminar, we describe the concept of a practical, three-pronged approach for rapid method development. More...	Upcoming Events   16–21 June 37th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2012) Anaheim, CA » Visit the website   18–21 June BIO International Convention Boston, MA » Visit the website   15–18 July PREP 2012 International Symposium on Preparative and Process Chromatography Boston, MA » Visit the website   12–17 August XXI International Materials Research Congress (IMRC) 2012 Cancun, Mexico » Visit the website   9–13 September 29th International Symposium on Chromatography (ISC) Torun, Poland » Visit the website   11–14 September 9th Symposium on the Practical Applications of Mass Spectrometry in the Biotechnology Industry (Mass Spec 2012) San Diego, CA » Visit the website   30 September–3 October International Symposium on Preparative and Industrial Chromatography and Allied Techniques (SPICA 2012) Brussels, Belgium » Visit the website   30 September–4 October CE in the Biotechnology & Pharmaceutical Industries: 14th Symposium on the Practical Applications for the Analysis of Proteins, Nucleotides, and Small Molecules Scottsdale, AZ » Visit the website   21–24 October 4th International Conference on Polyolefin Characterization Houston, TX » Visit the website   25–30 November Materials Research Society (MRS) Fall Meeting & Exhibition Boston, MA » Visit the website