The LCGC Blog
I'm often asked: “what reproducibility should I expect to get from my [insert instrument manufacturer and model]?” So, most folks are referring to the repeatability aspects of precision, as in: “what relative standard deviation (usually expressed at %RSD) for peak area or quantitative result should I be able to achieve from repeat injections from a single vial of sample?”
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Understanding charge variance of biopharmaceuticals or biosimilars is critical to ensure drug efficacy and safety. We've made this process easier and faster for you with our patented  Thermo Scientific CX-1 pH Gradient Buffer Kits. Enter our competition to win a kit AND get a discount!
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Space-based and time-based separations are often a preferred approach. Peter Schoenmakers from the University of Amsterdam discusses how they can be combined and the benefits of this approach. He also discusses the complexities of 3D LC. Read more
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The Restek PAL SPME Arrow system is a revolutionary change in microextraction that combines exceptional robustness with faster extraction times and trace-level sensitivity. In contrast to traditional SPME fibers, SPME Arrows contain significantly more phase volume, which allows more target analyte to be extracted in less time, substantially increasing sample throughput.  Learn more
Featured Article
This yearly report on new products introduced at Pittcon 2017 (or in the preceding year) covers sample preparation instrumentation, supplies, and accessories. Read more
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While scientists have known about the presence of chiral molecules for more than 150 years, the field of chiral chemistry is far from stagnant—especially in the world drug design and development. Given the serious problems that can occur if enantiomeric impurities are present in a drug, developers need to keep abreast of the newest techniques for fast and effective chiral separations.  Download Your Free eBook
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The HILICON® iHILIC® Fusion chemistries in both column and SPE formats, address more and more polar molecule isolation challenges. Desalting with TARGA® C18, BioPureSPN™ SPE from 100% water will improve recovery of these polar molecules prior to LCMS. Try one of our  Fusion or TARGA separation approaches today! The Nest Group, Inc. - “Not Just Columns ... Answers!”
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An annual review of new developments in the field of gas chromatography (GC) seen at Pittcon 2017 and other venues in the past year. Read more
Well-established techniques used by the food safety industry, such as QuEChERS sample preparation followed by LC–MS/MS for the analysis of multiresidue pesticides, are evaluated for use with cannabis plant material.We evaluated a modified QuEChERS LC-MS/MS method for analysis of multiresidue pesticides. Read more
The method presented here allows for the accurate, precise, and robust speciation, profiling, and quantification of cannabinoids in hemp oil extracts and commercial cannabinoid products for research and development laboratories. Read more
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Application Note
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SPE procedure coupled with LC–MS/MS detection is simple and robust, providing highly accurate and reproducible results for a multiresidue pesticide analysis.  Read more
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