The LCGC Blog
Modern HPLC method development is dominated by a small number of pH adjusting reagents and buffers that are prevalent even when the method uses UV detection. This is driven primarily by the requirements of mass spectrometry.
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Protein-Ligand Library Screening
Shorten the timeline between target and hit identification. A proven LC-MS coupled column, automated binding assay, allows ˜12K compound/week, low hit rate library screening. Try this solution-based, affinity selection, SEC-RPC coupled column assay today!
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Featured Articles
In recent years, there has been a paradigm change in the way we approach mobile-phase design for high-performance liquid chromatography (HPLC). What are the trends?
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Legacy LC methods seem like they come from a different planet. This month, we look at which conditions to keep, and which ones to let go.
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LenS3™ MALS Detector
The new LenS3 MALS detector features an innovative flow path and optics design that maximize the collection of the scattered light, while minimizing noise from stray light. The resulting unprecedented sensitivity allows the detection of extremely low molecular weight and quantity of sample, as well as the measurement of size (radius of gyration) below 10 nm for the first time by SEC-MALS.
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New HPLC and MS systems: A review of instrumentation trends and the current market along with new instruments, modules, chromatography data systems, and related software.
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Micro Pillar Array Column Technology Resource Center
An online resource with useful tools and practical information for separation scientists who want to find out more about how micro-pillar array columns can benefit the laboratory scientist in practice. The site provides useful technical notes, video interviews, and executive summaries of cutting-edge applications from leading practitioners in the field of proteomics and biopharmaceutical applications.
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In this interview, Thomas Letzel of the Technical University of Munich considers the current state of water analysis, looking at recommended techniques, the growth of nontargeted screening, and multi-disciplinary collaboration.
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Exclusive Interview from Pittcon
The Next Generation in Light Scattering for Absolute Macromolecular and Nanoparticle Characterization
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Featured News
Researchers have analyzed sediment core from a lake located in the northern foothills of Alaska's Brooks Range to investigate the Beringian standstill hypothesis (BSH) of human migration into the Americas.
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FEATURED PRODUCTS
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DAICEL now offers a full set of sub-2 micron columns: CHIRALPAK© IA, IB, IC, ID, IG, and IH. This full set offers ultrafast separations, higher resolution power, and results in seconds.
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This high speed, benchtop centrifuge has a specially designed rotor & adapters to accommodate 12x32mm, heavy wall, autosampler vials. Useful when contaminants from plastic must be avoided or low volume centrifugation is needed.
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Centri® – a multi-technique sample automation, pre-concentration and injection platform for GC that delivers enhanced analytical sensitivity and higher throughput for VOC and SVOC analysis in liquid, solid and gas samples.  / Learn more / |
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COSMOSIL SFC columns have been developed to enhance SFC separations, with 6 stationary phases for high- and low-polarity compounds and unique separations using secondary interactions.
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WinGPC software for GPC/SEC, IPC and 2D-LC enables compliance with FDA21CFR11 also for (multi angle) light scattering and viscometry. WinGPC can control different LC systems or load/process CDS data (e.g. Chromeleon™ 7.2).
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Proton OnSite's Nitrogen Lab Servers produce up to 400 SLPM of high purity nitrogen from external compressed air sources. They are space-saving solutions that maintain quiet, steady operation.
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