LCGC Blog

The LCGC Blog: Time Interval Deconvolution as an Alternate Strategy to Peak Integration Using Gas Chromatography–Vacuum Ultraviolet Spectroscopy

Precise and accurate quantitative analysis based on chromatographic measurements has historically relied very heavily on careful peak integration. Seasoned analysts know that while automated algorithms exist in modern chromatography software, it is a best practice to manually check that the integration points—the points at the beginning and end of a peak, between which the peak will be integrated to obtain a peak area—are appropriately specified. Read more

Fast, Zero DCM Sample Cleanup for POPs Analysis

A new automated cleanup system allows for fast cleanup of Dioxins and PCBs (30 minutes). Solvent consumption is limited to 110–200 mLs depending on sample lipid content. No dichloromethane is used during the cleanup steps. Sample analysis turnaround times in a few hours. More Information

LCGC TV

Extra-Column Band Broadening in Gradient and Isocratic Separations

In both gradient and isocratic separation modes, the most problematic part of the extra-column band broadening is behind the column. Gert Desmet from the Vrije Universiteit Brussel discusses his recent findings and offers his advice to chromatographers. Read more

Focus on Petroleum Analysis: Battling Fuel Fraud and Achieving ASTM D5769

Costing an estimated $100 billion annually worldwide, fuel fraud has been difficult and expensive to combat. Learn how new analytical techniques can both help battle fuel fraud and easily satisfy ASTM method requirements. Download the Executive Summary

Featured ArticleS

The Secrets of Successful Gradient Elution

What is required to optimize a gradient elution HPLC method? Read more

Count the Cost, Part III: Increasing Resolution by Changing Selectivity

To change selectivity in LC, which variable should you choose? Read more