May 10,2018

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May 10, 2018

The LCGC Blog

The Shape of Things to Come: Possible Changes to USP Chapter <621>

It's excellent to see that compendial authorities are considering updating "allowable change" regulations, and the updates to allow changes to gradient profiles certainly open up a whole new world, but there are some reservations around the new restrictions on allowable changes to stationary-phase chemistry. Read more

Ultimate Protection for 1.8 µm Raptor Columns

New EXP UHPLC guard column cartridges are made specifically for Raptor 1.8 µm columns. They provide extreme protection from particulates and matrix contamination, extend the lifetime of already rugged and long-lasting Raptor columns, and are proven to withstand the same UHPLC pressures as their analytical column counterparts. These new guard column cartridges are especially valuable when using dilute-and-shoot or other minimal sample preparation techniques. Read more

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Featured Articles

New Chromatography Columns and Accessories for 2018

Our annual review of new liquid chromatography columns and accessories, including columns for reversed-phase, HILIC, chiral, SEC, GPC, ion-exchange, and SFC separations of small and large molecules. Read more

Join Agilent at ASMS 2018!

Pre-Game with Agilent before the start of the show at our Saturday Innovation Symposium on June 2!
The event begins with a dinner and drink reception, followed by presentations from leading scientists in key areas of research. Be sure to also save your seat at our 3 breakfast sessions happening in our hospitality suite throughout the week. Learn more

Best Practices for Analyzing Pesticides and Their Metabolites in Environmental Samples

James Stry of FMC Agricultural Solutions talks about best practices for developing robust environmental analysis methods, including simplifying sample preparation and dealing with matrix effects. Read more

Data Integrity in the GxP Chromatography Laboratory, Part II: Setting up a Chromatograph and Acquiring Data

Part II of this series on practical perspectives on data integrity focuses on instrument setup, system suitability test samples, and data acquisition. Read more

Trends and Developments

A snapshot of key trends and developments in the chromatography sector according to selected panelists from companies who exhibited at Analytica 2018. Read more

Liquid Chromatography Tandem Mass Spectrometry Method for Novel Psychoactive Substances: Kratom and Synthetic Cathinones in Urine

A novel "dilute-and-shoot" LC–MS/MS method is described for the analysis of "bath salts" sold as "legal" highs, including mitragynine and nine synthetic cathinones, in urine. Read more

Hamilton HPLC Application Index - Online!

Three easy steps and you have access to almost 1400 compounds that have been separated on Hamilton polymer-based HPLC columns.

Compounds are listed alphabetically
Keyword search makes it even easier to get the chromatograms and separation conditions
Get valuable literature references

Check out Hamilton's online HPLC Application Index today! Learn more

Application Note

IDP Scroll Pump Evaluation on MS

This application note compares the Agilent IDP-10 Dry Scroll Vacuum Pump and Oil Roughing Pump on the Agilent Intuvo coupled to the 7010B Triple Quad MS. Learn more

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SEC-MALS Detector

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Separation & Characterisation of Charged Molecules

Postnova Analytics announces the launch of the EAF2000 - an innovative new simultaneous Electrical and Asymmetrical Flow Field Flow Fractionation (EAF4) system designed to enhance separation and characterisation of biopharmaceutical, environmental and nanomaterials. Learn more

Laboratory solvent bottles

InfinityLab solvent bottles from Agilent, available through Neta Scientific, are designed for easy and safe handling. According to the company, the 1- and 2-L bottles are ergonomically designed with gripping zones on the sides, and stay-safe caps prevent solvents from leaching into the air. Neta Scientific, a distributor for Agilent Technologies, Hainsport, NJ. www.netascientific.com

Discrete Dynodes from Photonis

Photonis Discrete Dynode Electron Multipliers offer continuous high dynamic range from single ion to high concentrations through a dual-stage analog and pulse counting design that improves sensitivity, air stability and long life. Learn more

Plan C: Chemistry

A must-read for analytical chemists. It explains impactful instrument designs, compares corporate cultures, and offers best practices in management. It also comes with augmented reality videos. Available on Amazon.com

New Webcasts

LC–MS Workflows for Veterinary Drug Testing Laboratories

Sequence Your Biopharma N-Glycans in as Little as 1 Hour

What Does ISO 17034 Mean for Your Laboratory?

Tuesday, May 15, 2018 at 2 pm EDT | 1 pm CDT | 11 am PDT | 11 am MST
Register>>

Quantitative Odor Monitoring: Source to Fenceline Analysis Using Direct MS

Europe Broadcast: Wednesday, May 16, 2018 at 1300 BST | 1400 CEST
US Broadcast: Wednesday, May 16, 2018 at 11 am EDT | 10 am CDT | 8 am PDT
Register>>

Address the Paradigm Shift in Regulatory Inspections

Updated USEPA Approved Method for the Analysis of Nitrosamines in Drinking Water Using GC–MS/MS

The CHROMacademy Essential Guide Webcast: Choosing the Right Column for Intact Protein Characterization – a Deeper Dive into Column Characteristics