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| The LCGC Blog |
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Four Steps to Troubleshooting an HPLC Problem
What do you do when the go-to expert in your lab gets laid off, and is no longer there to help solve your HPLC challenges? Do you spend precious time hunting for the solution online, or by asking colleagues, vendors, and service providers for advice? The situation prompted development of an approach that can help troubleshoot your HPLC problems in four steps. |
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| Live Webinar on April 23, 2015: Maximize Laboratory Efficiency |
Join Agilent’s live webinar and learn how to optimize your laboratory’s workflow and to meet varying workload demands and short turnaround times. Understand how to embrace change management in your laboratory to adapt to organizational centralization and standardization.
 Register now: http://EfficientUHPLC.agilent.com
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| LCGC TV |
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Kevin Schug on Trace Analysis of Estrogen Using 2D LC–MS–MS
Estrogen can have a big effect on physiological processes in the human body, even when present at trace levels. In this video, Kevin Schug, from the University of Texas at Arlington, talks about the advantages of using restricted access media for the on-line sample preparation of biofluids in a “trap-and-elute” LC–MS arrangement, and the potential of this approach for other applications. |
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| Improve Your Mass Spec Workflows |
Join us for a free webinar April 23rd at 9:30 (EDT) to learn how to Improve Your Mass Spectrometry Workflows with the New NIST Software, Featuring the Wiley 10th/NIST 2014 hosted by Prof David Sparkman.
Webinar will cover; Compatibility and systems interface tips, Retention time workflow, LCMSn workflow, , Accurate mass workflow, Search strategies, Compound coverage strategies
 Sign up today! |
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| Featured Articles |
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Be Careful of the Flow Rate
When converting methods from liquid chromatography to ultrahigh-pressure liquid chromatography, don't get confused by flow-rate settings. In this installment of LC Troubleshooting, columnist John Dolan discuss situations when changes in flow rate are fairly innocuous and when they can get you into trouble. |
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| Compact Single Channel GC |
The 200 series GC from Ellutia is a cost effective single channel gas chromatograph. Available with a choice of detectors (FID, TCD, ECD or FPD), a split/split-less injector and full programmable pressure control. The compact footprint also makes it ideal for laboratories where space is of a premium.
 Find out how a 200 Series can help with your analysis today. |
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Understanding Electron Ionization Processes for GC–MS
Many of us use electron ionization (EI) in gas chromatography–mass spectrometry (GC–MS) without a good understanding of the technique and how we might manipulate the process to give more appropriate results or a better understanding of the analytes under investigation. Here, we explain the fundamental principles of EI. |
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| Metabolomics: Prospects and Pitfalls |
Prof. Oliver Fiehn, PhD, Director of the NIH West Coast Metabolomics Center, University of California, Davis, explains steps to follow in the metabolomic workflow and addresses common metabolomic questions in a new LCGC e-Book.
 Click here to download.
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Photo Credit: Jason Teale Photography/Getty Images
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GC Troubleshooting in Petrochemical Analysis
Gas chromatography is a core analytical technique in the petrochemical sector, primarily used to analyze the main process stream components in fuel production but also to detect trace impurities that can impact the production process and final product. This is your guide to simple troubleshooting steps in gas chromatography with an emphasis on petrochemical analysis. |
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CHROMacademy offers video training courses to its members – Fundamentals of GCMS starts May 7!
 Learn more
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| Featured Products |
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| TLC: We have you covered |
New OMNISEC GPC/SEC System |
There's only one Millex® filter. |
EMD Millipore's TLC plates combine adherence, hardness, and surface homogeneity for unsurpassed separation. They are available in various formats, backed in glass, aluminum or plastic, with or without a fluorescent indicator.
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For absolute molecular weight characterization of synthetic and natural polymers, as well as determination of aggregation and oligomeric state of proteins with the lowest of sample concentration requirements.
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Don't be fooled by other filters, which may show unpredictable performance. EMD Millipore’s history of membrane technology and device engineering is unmatched. See the difference—request a free sample Millex® filter.
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| Combustion Ion Chromatography |
Graphing and Analysis Software |
Metrohm's Combustion IC (CIC) simultaneously determines halogens and sulfur in a wide variety of matrices. CIC can separate and quantitate different halogens with much higher sample throughput, accuracy and precision.
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Origin software provides a comprehensive solution for scientists and engineers to analyze, graph, and professionally present data. Origin is used by over 500,000 users in corporations, government agencies, and academia.
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