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The LCGC Blog
As I've written previously, our Nirvana in HPLC column selection would be to enter the structures of our analytes and have a database tell us the column and mobile phase conditions that we should use to carry out the separation successfully. Although I know of several groups who are working on this, in practice we are still a long way from realizing this goal. Read more
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New generation Jordi GPC columns prepared with monodisperse 100% DVB particles with precisely controlled particle diameter and finely controlled pore structure provide high efficiency, high separation capacity, low back pressure with greater bed stability & clean light scattering backgrounds. Resolve columns allow separation from 500 to 12 million g/mol (PS equivalent).
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While scientists have known about the presence of chiral molecules for more than 150 years, the field of chiral chemistry is far from stagnant—especially in the world drug design and development. Given the serious problems that can occur if enantiomeric impurities are present in a drug, developers need to keep abreast of the newest techniques for fast and effective chiral separations.  Download Your Free eBook
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There has been an increase in interest in hydrophobic interaction chromatography (HIC) for protein separations. Alain Beck from the Center of Immunology Pierre Fabre discusses his proposed workflow for the separation of monoclonal antibodies and antibody-drug conjugates. Read more
More Featured Articles
Changing just one variable at a time is often the best approach. Read more
Discriminant analysis is an approach that deserves more attention. Read more
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Featured Articles
This is the second in a series of articles exploring current topics in separation science that will be addressed at the HPLC 2017 conference in Prague, Czech Republic, from June 18–22. Read more
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Eliminate analyte chelation of ferric atoms and wasted LC-MS time from lost or tailing peaks! Sprite™ columns and HAIPEEK™ cartridges deliver the best performance from your system. Try TARGA®, CLIPEUS™ and PROTO™ 200 or 300 chemistries in our  Wide Range of PEEK Formats Or, we'll custom pack yours for you! The Nest Group, Inc. - "Not Just Columns ... Answers!"
New extraction techniques can improve the accuracy and precision of analytical results and simplify analytical procedures. Read more
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Are you ready to tackle the EPA's PAMS program? During this live webinar, we'll describe the Markes-Agilent Auto-GC set up for EPA PAMS analysis for ozone precursors, EPA air toxics analysis, and EPA TO-15. The session will explore how to optimize the method conditions for VOC air analysis, including water management techniques for humid air samples, and system solutions for online, canister and bag analysis.  Learn more
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