The LCGC Blog
Just as medical practitioners are able to discern worrying features from a variety of medical physics devices (electrocardiogram, electroencephalogram, ultrasound, for example), we need to develop the skill to identify worrying symptoms from our HPLC instrument output.
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• HPLC 101 provides definitions and terminology
• Answers to common questions when starting your column selection process
• "How-To" page helps you choose a product that's right for your application
• Care and Storage section advises on maximizing the life of your product
• Technical References include resin specifications and useful chromatography calculations
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Featured Articles
Whether or not headspace sampling is quantitative depends on the information gleaned from the analysis.
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Determining the higher order structure of a protein pharmaceutical is important. Here, we review the approaches for HOS determination that are currently receiving the most attention in the literature and at scientific meetings.
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New strategies for "bottom-up" analysis of therapeutic proteins, using faster enzymes, new buffer systems, and optimal column chemistries, enable analysts to perform these studies much faster and with fewer artifacts.
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The versatile size-exclusion ultrahigh-performance liquid chromatography (SE-UHPLC) platform method described here provides superior separation for bispecific monoclonal antibody formats compared to a previous method.
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By taking simple proactive troubleshooting steps, GC users can ensure that instruments will operate correctly over time, thus avoiding workflow disruptions.
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Are you aware of the risks involved in using a quantitative reference standard designed for qualitative use only? Learn about characterization of reference standards. / Read more / |
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