As we begin 2019, the LCGC editorial team looks back at some of the most popular separation science articles of 2018.

1.Data Integrity in the GxP Chromatography Laboratory, Part I: Sampling and Sample Preparation

Part I of this series on practical perspectives on data integrity focuses on sample management, transport, and preparation.
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More of What You Need to Keep Your LC Flowing

Restek has expanded our line of LC accessories to bring you even more of what you need to keep your LC flowing. Browse top-quality couplers, fittings, unions, tees, and crosses; PEEK and stainless steel tubing; mobile phase maintenance and safety products including bottle tops, valves, filters, and spargers—and that's on top of our already wide selection of instrument replacement parts and supplies. Don't stop at the column; outfit your entire LC system with Restek LC products. Read More

The Proton OnSite Hydrogen Lab Server produces up to 18.8 SLPM of ultra-high purity hydrogen gas sensing demand and adjusting production accordingly. When installed into a gas system, it can serve numerous floors and rooms with a constant, pure stream of hydrogen gas. This compact generator produces the equivalent of four cylinders of hydrogen every day – eliminating the cost and hazards associated with delivered gas. Read More

3. Charge-Variant Profiling of Biopharmaceuticals

A look at techniques for charge-variant analysis of monoclonal antibodies and the question of whether pH gradients are really better than salt gradients. Read More

Techniques for Improving Biopharmaceutical LC–MS

The analysis of biopharmaceutical compounds is complicated for numerous reasons. This ebook explores how analysts can address some common issues related to the analysis of biomacromolecules like monoclonal antibodies and antibody–drug conjugates. Download your free ebook

4. Current and Future Chromatographic Columns: Is One Column Enough to Rule Them All?

The packed particle bed format still rules LC columns, but advances continue in monoliths. Meanwhile, newer formats are on the horizon, including microfabricated columns and 3D printed columns. This article provides a critical review of all these technologies and demonstrates how further development of chromatographic columns will be of paramount importance in the future. Read More

The longest running, most technical scientific conference in the cannabis industry

Devoted exclusively to Exploring the Science of Cannabis, the 5th Annual Emerald Conference takes place February 27-March 1, 2019, at the Loews Coronado Bay Resort in San Diego. Focusing on Analytical Testing, Clinical Research, Extraction, Formulations, Genotyping and Chemotyping, the conference features industry-leading speakers, a charity golf tournament, world class food and networking receptions. Read More