LCGC North America Application Note Alert
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Quantitation and Clean-Up of Neutral and Sialylated Glycans
A HILIC solid phase extraction (SPE) and LC method that results in sensitive, effective, and time savings for the clean-up of N-Glycans.
Easy Method Development for Bioanalytical Therapeutic Peptides
Implementing a peptide screening SPE plate determines the appropriate choice for a wide range of chemically diverse peptides.
Solid-Phase Extraction Method to Reduce Surfactant Interference
The optimized dual solid phase extraction (SPE) method was developed to significantly reduce the surfactant background from formulated drug products.
Fast Determination of Ibuprofen in Human Plasma
A fast analytical method including both sample preparation and LC–MS/MS analysis of ibuprofen in human plasma.
Chiral LC–MS/MS Analysis of Amlodipine Enantiomers in Plasma
The development of a selective and rugged LC–MS/MS method for the quantitation of Amlodipine enantiomers in human plasma.
Analysis of Opiates from Urine Using Large Reservoir Cartridge SPE
SPE is used in combination with LC–MS/MS to analyze a panel of opiates from a urine sample.
In-Well Hydrolysis SPE for Drugs of Abuse from Urine
Optimize the LC–MS/MS workflow by using a SPE solution that provides in-well urine hydrolysis to save time.
Determination of Mycotoxins Using Solid-Phase Extraction and LC–MS/MS
Mycotoxin in grain are extracted using SPE to removes interferences followed by a rapid LC–MS/MS method.
PFAS and GenX from Water by SPE and LC–MS/MS
GenX, along with 24 other PFASs, are analyzed simultaneously to achieve sub-ppt reporting limits.
Determination of Sterols in Olive Oil
A reliable and efficient method was developed to determine the concentration sterols in olive oil by GC-FID.