LCGC North America Application Note Alert
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LCGC Global
Characterization of Intact mAbs by 6545XT AdvanceBio LC/Q-TOF
A workflow using the Agilent 1290 Infinity II UHPLC system, 6545XT AdvanceBio LC/Q-TOF, and MassHunter BioConfirm software to analyze a variety of mAb products
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Workflow for Mass Measurement of Intact and Subunits of mAbs
Demonstrates a streamlined approach for accurate mass measurement in the analytical characterization of intact mAbs using the Agilent AssayMAP Bravo platform.
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In-Depth Peptide Mapping with Iterative MS/MS
This Application Note presents an integrated workflow for peptide mapping of a mAb from automated sample preparation to data analysis.
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Comprehensive mAb N-Linked Glycan Analysis
An automated process for highly sensitive N-linked glycan analysis using fluorescence and additional identification by mass spectrometric detection.
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Profiling Glycosylation of mAbs at Three Levels
This app note demonstrates a complete and automated workflow solution for antibody glycoforms characterization.
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Unique UV-Vis Characterization of mAb Aggregation
A quick QC method to indicate the presence of aggregation is presented in this study using an Agilent Cary 60 UV-vis spectrophotometer.
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Method for High-Resolution Separation and Quantification of mAbs.
This Application Note describes a simple and sensitive method for the quantitative analysis of monoclonal antibodies (mAbs) by SEC.
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Charge Variant Analysis of Rituximab Innovator and Biosimilar
This Application Note shows the analysis of charge variants for the innovator as well as for the biosimilar of rituximab.
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Optimizing Protein Separations with Cation-Exchange Chromatography
Agilent Buffer Advisor software with the Agilent 1260 Infinity Bio-inert Quaternary LC System is ideal for automated protein separation by ionic strength gradients.
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Automated and Sensitive HCP Analysis
An HCP analysis workflow using the Agilent AssayMAP Bravo platform for automated sample preparation and the Agilent 6545XT AdvanceBio LC/Q TOF for LC-MS/MS analysis.
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UBM