LCGC North America Application Note Alert Having trouble viewing this email? Click here SEC Identifying Short-Chain Branched Polymers Short- and long-chain branching in polymers are distinguished and quantified by SEC coupled to multi-angle light scattering and differential viscometry detectors.   LC-MS Reduce Peak Dispersion in HPLC/UPLC Set-Ups Post-column flow splitting can cause excessive peak broadening and reproducibility issues for LC–MS scientists, but this can be solved using modern splitting technology. Metal-Free Columns for Troubleshooting Phosphorylated Compounds Phosphorylated compounds adsorb to stainless steel, negatively impacting peak shape, sample recovery, and sensitivity. Our metal-free columns can improve analysis. Simultaneous Analysis of Catecholamines and Metanephrines in Urine by LC-MS/MS Analysis of these polar compounds using reversed-phase LC can be difficult due to limited chromatographic retention, which results in poor separation of the analytes from closely eluting matrix interferences.   Sample Prep Analysis of Oxygenates and Aromatics Using ASTM Methods This study shows how PerkinElmer’s Arnel Model 4004 GC Analyzer provides greater flexibility and productivity for ASTM testing methods D4815 and D5580. LipiFiltr® Clean-Up of Oil-Based Cannabis Products This application note outlines the performance benefits of using the new LipiFiltr® cartridge in applications involving pesticide analysis of oil-based cannabis products. Eliminate Toxic Contaminants from Cannabis Extracts Learn simple, cost-effective, proven procedures to eliminate toxic contaminants from cannabis extracts, while maintaining yield and purity of valuable cannabinoids. Water-soluble Vitamin Analysis A method to simultaneously analyze various water-soluble vitamins using a Shodex DE-413L, a polymer-based reversed phase column, without a use of ion-pair reagent   GC-MS Polymer Analysis Using the Pyroprobe 6000 Series The latest version of the Pyroprobe includes easier sample preparation and introduction with the new DISC (Drop In Sample Chamber) coupled with DISC sample tubes. Comparison of the aroma profiles of hops This study demonstrates the high performance of a dynamic headspace sampler with TD–GC–TOF MS analysis for investigating the complex aroma profiles from hops.   LC Analysis of Apramycin Sulfate Post-column derivatization with Ninhydrin reagent for analysis of 3-hydroxyapramycin, lividamine, caerulomycin, 2-deoxystreptamine as impurities in Apramycin Sulfate. Peptide Analysis with 1.6 µm Columns The Develosil UHPLC series gives sufficient retention and separation while using ammonium formate for the mobile phase; it can produce useful results in LC–MS. Fast Separation of Triptans in Rat Plasma on ZirChrom®-PBD The following reviews a published comparison of the ZirChrom®-PBD column to the HypersilTM BDS C18 column for the analysis of triptans in rat plasma.   HPLC Guide for Successful (U)HPLC Method Transfer Method transfer is a common practice in HPLC. Read about instrumental parameters, challenges, and solutions to consider during the transfer of an analytical HPLC method. Switching from Helium to Hydrogen Made Easy Switching from helium to generated hydrogen as a GC carrier gas and detector fuel can save labs a lot of money, improve GC testing, and optimize laboratory operations.