LCGC North America Application Note Alert
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LCGC Global
HPLC
Monitoring of Mammalian Cell Culture Media
This application note describes the monitoring of nutrient uptake and excreted waste products in mammalian cell culture media with HILIC LC–MS.
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Novel Stationary Phase Fights Cardiovascular Disease
LC–MS methods are challenging because they are isomers with the same m/z. We show successful separation on a novel stationary phase without derivatization.
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Rapid Separation of Basic Drug Compounds Under Alkaline pH Conditions on pH-Stable, Hamilton PRP™-C18
In this study a generic, 5-min linear gradient was used to separate six basic drug compounds on a short (50 mm) PRP-C18 column.
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Sample Preparation
LipiFiltr® Cleanup for High-Lipid Food Samples
The application shows the benefits of using the LipiFiltr® cartridge in multi-class, multi-residue analysis for a wide range of pesticides in complex, high fat samples.
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General
Characterization of Protein-DNA Complexes
Quantifies affinity, stoichiometry of biomolecular assemblies, helping understand the mechanism of interaction and develop therapeutics that target and modulate them.
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LC/HPLC
Simultaneous Analysis of Monoclonal Antibodies
The Thermo Scientific Vanquish Duo system for Dual LC can run two methods simultaneously on one instrument, regardless if identical chromatographic conditions are used.
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UBM