LCGC North America Application Note Alert
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HPLC
Developing Strategies for Preparative HPLC
This technical overview describes how to combine UV- and mass-based fraction detection with recovery collection for confident, successful sample purification.
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Multiclass Residue Analysis of Veterinary Drugs
This application demonstrates a quick and easy method to analyze 151 veterinary drugs across 27 classes in pork and hen eggs using Agilent Ultivo Triple Quad LC/MS.
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HPLC Determination of CBD and General Cannabinoid Content in Hemp Oils
This application note highlights the use of a High Sensitivity HPLC method to determine 11 important cannabinoids, including CBD, in hemp oil.
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Separation of Naproxen Using CHIRALPAK® IH / IH-3
CHIRALPAK AS-H and CHIRALPAK IH were used in an optimized HPLC method to separate naproxen, focusing on selectivity, resolution, and productive in a preparative method.
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Analysis of Fentanyl in Human Urine by LC-MS/MS
Synthetic opioid drugs, such as fentanyl and sufentanil, have very high analgesic potency. Abuse of these prescription painkillers—along with a rapidly growing list of illicit analogues—is a significant public health problem. In this study, we developed a simple dilute-andshoot method that provides a fast 3.5 minute analysis of fentanyl and related compounds (norfentanyl, acetyl fentanyl, alfentanil, butyryl fentanyl, carfentanil, remifentanil, and sufentanil) in human urine by LC-MS/MS using a Raptor Biphenyl column.
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GPC
Determination of copolymer composition and molar mass
Co-polymers cannot be characterized by standard GPC. The addition of MALS, UV and RI detectors provides accurate distributions of molar mass and co-polymer fractions.
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Hyphenated
LC-MS/MS Detection of Fentanyl and Related Synthetic Opioids in Biological Matrices
This application highlights the development of a single LC-MS/MS method to identify and determine a limit of detection for several synthetic opioids, including fentanyl.
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Sample Prep
5 Minute Pesticide Extractions
This application note demonstrates a new technology for 5 minute extraction of pesticides from difficult food matrices.
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Analysis of Glyphosate, Glufosinate and Metabolites Using UCT’s Enviro-Clean® Glyphosate Push-Thru Purification Cartridge
Glyphosate (N-(phosphonomethyl)glycine) is a broad-spectrum systemic herbicide and crop desiccant that is used to kill weeds and grasses that compete with crops. While glyphosate formulations have been approved by regulatory bodies worldwide, concerns about its effects on humans and the environment have grown as the global usage of glyphosate has increased. As a result, glyphosate now finds itself at the forefront of agricultural regulatory testing. UCT’s Enviro-Clean® Glyphosate Push-Thru Purification Cartridge simplifies the analysis of glyphosate and its metabolites by removing unwanted matrix components that can otherwise lead to significant ion-suppression.
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GC
E&L Analysis Using GC/MSD Systems
Plasticizers were identified in pharmaceutical formulations using GC/MSD
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UBM