LCGC North America Application Note Alert Having trouble viewing this email? Click here Featured Application Note Best Practices: TLC Before Flash Chromatography Illustrating “best practices” use of TLC prior to flash chromatography with simple examples, including definitions of RF, CV, and use of gradient chromatography and gradient flash chromatography.   Hyphenated Screening Analysis of Highly Polar Doping Agents in Urine Using 2D LC–MS/MS This application note highlights 2D LC–MS/MS for the simultaneous analysis of highly polar doping agents and adrenergic agents.   HPLC Optimizing Investigative Monitoring of Emerging Contaminants HPLC retention time (tR) prediction using ACD/ChromGenius can significantly improve efficiency in investigative monitoring of emerging environmental contaminants. Hamilton PRP™-C18 High-Efficiency Separations at Any pH The pH stability of the PRP-C18 is evaluated. Even after prolonged exposure to concentrated (1 molar) NaOH and H2SO4 there was no measurable deterioration in performance. Separation of THC Isomers on Cogent C18 THC has several isomeric forms that can be separated from the main peak using the Cogent Bidentate C18 column with a high amount of organic solvent, easily and precisely. Shodex LB-806M Column for Heparin Analysis Shodex promotes LB-806M for its negligible bleed using MALS detection, which can detect a wide range of molecular weight compounds. Heparin was used as an example. Cannabis Potency Using Low-Cost HPLC A simple isocratic HPLC method for the testing of Cannabis. The DLC-10 is a small footprint, easy to use and low-cost HPLC system. The included fixed wavelength detector has good signal response when using the 214 nm Zinc lamp.   Sample Prep Automated Integrated Workflow for ADC DAR Characterization Easy-to-use and fully-integrated method for the determination of drug-to-antibody ratios (DARs) of antibody-drug conjugates (ADCs). Per- and Polyfluoroalkyl Substances (PFASs) in Drinking Water A simple SPE procedure for the extraction of 26 diverse PFASs in drinking water using UCT’s polymeric weak-anion exchange SPE cartridges (ENVIRO-CLEAN® WAX). 5 Minute EPA 3545 Extractions This application note demonstrates a new technology for 5 minute extraction of semi-volatile organic compounds from soil in accordance with EPA 3545.