In our March issue:
COLUMNS
LC Troubleshooting
Troubleshooting LC Separations of Biomolecules, Part I: Background, and the Meaning of Inertness
Jordy J. Hsiao, Gregory O. Staples, and Dwight R. Stoll
How do I know when bioinert liquid chromatography columns, systems, or components are needed for my separations of biomolecules?
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GC Connections
Go With the Flow: Thinking About Carrier Gas Flow in GC
Sean P. McCann, Hetal Rana, Brittany A. Handzo, and Nicholas H. Snow
Successful GC analysis requires careful control of carrier gas. Here, we explain how to measure and control flow rate, use constant pressure vs. constant flow, and more.
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MCF Spring Symposium features three technical classes: “CSI GCMS-Style” “GC Method Development” and “LC Method Development”.
The Keynote will be given by Dr. Kevin Schug of University of Texas at Arlington. Also included are a vast technical program, poster session, door prizes, food, beverages, and FREE BEER! The MCF Spring Symposium is also the upper Midwest’s largest Chromatographic instrumentation and supplies exhibition.
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Sample Prep Perspectives
Sample Preparation in the Rearview Mirror: Looking Back on 2019
Douglas E. Raynie
This selection of influential recent papers on chromatographic sample preparation gives us a sense of important developments.
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Understanding Oligonucleotides from Every Angle: Utilizing Mass Spectrometry for Characterization and Quantification
Tuesday, March 17, 2020 at 11am EDT | 8am PDT | 3pm GMT | 4pm CET
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Fundamentals
HPLC Diagnostic Skills—Noisy Baselines
Tony Taylor
To avoid producing data not fit for purpose, chromatographers need to know how to identify worrying symptoms from HLPC instrument output.
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Complete Workflow Solutions for Analyzing Complex Food Samples Using SPME
Tuesday, March 17, 2020 at 11am EDT | 8am PDT | 3pm GMT | 4pm CET
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PEER-REVIEWED ARTICLE
Hydrophilic-Interaction Chromatography: An Update
David V. McCalley
This review addresses recent ideas on the separation mechanism of HILIC, the advantages and disadvantages of the technique, and new applications.
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Exploring Faster GC Solutions for PAH and Priority Pollutant Analysis in Food and Environmental Samples
Thursday, March 19, 2020 at 11am EDT | 8am PDT | 3pm GMT | 4pm CET
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FEATURE ARTICLES
The Why, What, and How of CDS Audit Trail Review
R.D. McDowall
Examination of audit trail entries is a key part of the second-person review. What do regulatory documents say about this topic, and how can we speed up review?
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Testing Nitrosamine Content in Pharmaceutical Products
Tuesday, March 24, 2020 at 11am EDT | 8am PDT | 3pm GMT | 4pm CET
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Advancing Separation Science Throughout a Lifetime of Achievements: Daniel W. Armstrong, the Winner of the 2020 Lifetime Achievement in Chromatography Award
Jerome Workman, Jr.
Our interview explores Dan Armstrong’s career of contributions, spanning enantiomeric separations, molecular recognition, ionic liquids, ordered media, mass spectrometry, drug development, environmental research, and food analysis.
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Dealing with a Volatile Relationship: Using Purge and Trap and GC–MS to Improve Volatile Organic Compound Workflows
Wednesday, March 25, 2020 at 11am EDT | 8am PDT | 3pm GMT | 4pm CET
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Research in Protein Chromatography, Pharmaceutical Analysis, and Fundamental Studies in LC and Method Optimization: Szabolcs Fekete, the 2020 Winner of the Emerging Leader in Chromatography Award
Jerome Workman, Jr.
Szabolcs Fekete tells us about his work characterizing therapeutic proteins, studying liquid chromatography column technology, and optimizing methods.
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Market Profile
Flash Chromatography
Glenn Cudiamat
Flash chromatography is a purification technique that is designed for rapid separation by using air pressure as opposed to slow and inefficient gravity-fed chromatography. It differs from the conventional column technique by using slightly smaller silica gel particles and pressurized gas at 50–200 psi.
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Improve Productivity through Automated Ion Chromatography (IC)
Thursday, March 26, 2020 at 11am EDT | 8am PDT | 3pm GMT | 4pm CET
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Complete Workflow Solutions for Analyzing Complex Food Samples Using SPME
Tuesday, Mar. 17, 2020 at 11 am EDT | 8 am PDT | 3 pm GMT | 4 pm CET
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Editors’ Series: The CHROMacademy Essential Guide to: HPLC Method Troubleshooting
Wednesday, March 18, 2020 at 11 am EDT | 8 am PDT | 3 pm GMT | 4 pm CET
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Pesticide Analysis Using a GC-Triple Quadrupole Mass Spectrometer
Tuesday, April 14, 2020 at 11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
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If you would like to submit an article to LCGC, contact Laura Bush, Editorial Director - LBush@mmhgroup.com
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