In our January issue:
COLUMNS
Sample Prep Perspectives
Is Headspace Sampling Quantitative?
Douglas E. Raynie
Whether or not headspace sampling is quantitative depends on the information gleaned from the analysis.
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Maximize LC Separation Performance
Incorporating core-shell technology, Shimadzu's Velox HPLC columns enable users to achieve increased separations and faster analysis times on any LC platform, while providing excellent lifetime for the most challenging sample matrices. Utilize Velox columns and achieve improved separation and detection, outstanding analysis and data integrity, reduced analysis costs, higher productivity, and increased sample throughput.
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LC Troubleshooting
What's Trending in LC Troubleshooting?
Dwight R. Stoll
We look at problems in LC that can be traced to contaminated solvents or reagents, and how sample solvent effects can lead to poor performance in HILIC.
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Achieving PEEK-like Performance on Stainless Steel HPLC Components with Bio-Inert CVD Coatings
Thursday, February 28, 2019 at 11am EST | 8am PST | 4pm GMT | 5pm CET
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GC Connections
Stopping GC and GC–MS Problems Before They Start
Nicholas H. Snow
By taking simple proactive troubleshooting steps, GC users can ensure that instruments will operate correctly over time, thus avoiding workflow disruptions.
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Native Mode Mass Spectrometry Analysis
Wednesday, February 27, 2019 at 11am EST | 8am PST | 4pm GMT | 5pm CET
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Focus on Biopharmaceutical Analysis
Methods and Purposes for Determining Higher Order Structures of Biopharmaceuticals
J. Auclair, A. Rathore, and Ira S. Krull
Determining the higher order structure of a protein pharmaceutical is important. Here, we review the approaches for HOS determination that are currently receiving the most attention in the literature and at scientific meetings.
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The Importance of Computer System Validation for Regulated Systems
Three Live Dates: Europe: Tuesday, February 26, 2019 at 2pm GMT | 3pm CET
North America: Tuesday February 26, 2019 at 2pm EST | 1pm CST | 11am PST
Asia Pacific: Wednesday, February 27, 2019 at 8:30am IST | 11am CST | 12pm JST
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The Essentials
Essential Theory of HPLC
The elution mechanisms for gradient and isocratic HPLC are fundamentally different from each other. Here is what you should understand about both.
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Expanded Mycotoxin LC–MS/MS Analysis in Cannabis Matrices
Thursday, February 7, 2019 at 11am EST | 8am PST | 4pm GMT | 5pm CET
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Feature Article
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Data Integrity Focus, Part 1: Understanding the Scope of Data Integrity
R.D. McDowall
There are many factors to consider in a data integrity and governance program. Fortunately, a simple diagram can help us understand what needs to be covered.
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Syringe Filters: Take the Guesswork Out of Selection
Wednesday, February 6, 2019 at 11am EST | 8am PST | 4pm GMT | 5pm CET
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PEER-REVIEWED ARTICLE
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Suspect Screening of Chemicals in Food Packaging Plastic Film by Comprehensive Two-Dimensional Gas Chromatography Coupled to Time-of-Flight Mass Spectrometry
Yelena Sapozhnikova and Eunha Hoh
The occurrence of additives like plasticizers in plastic food packaging has been documented, but information on their potential migration into foods is limited. In this pilot study, 2D GC–MS was used to identify chemicals extracted from a common stretch plastic film with a series of organic solvents. In total, 91 compounds were tentatively identified, including five PCBs.
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| LIVE WEBCASTS |
Syringe Filters: Take the Guesswork Out of Selection
Wednesday, Feb. 6, 2019 at 11 am EST| 8 am PST| 4 pm GMT| 5 pm CET
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The Importance of Computer System Validation for Regulated Systems
Live Europe: Tuesday, Feb. 26, 2019 at 2 pm GMT | 3 pm CET
North America: Tuesday Feb. 26, 2019 at 2 pm EST | 1 pm CST | 11 am PST
Asia Pacific: Wednesday, Feb. 27, 2019 at 8:30 am IST | 11 am CST | 12 pm JST
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Native Mode Mass Spectrometry Analysis
Wednesday, Feb. 27, 2019 at 11 am EST| 8 am PST| 4 pm GMT| 5 pm CET
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| ON DEMAND WEBCASTS |
A Multi-mode LC Approach to Biosimilar Characterization
On Demand
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A Rapid, Simple, and Efficient Extraction Method for Additives in Plastics
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Screen Hundreds of N-Glycans per Day: More Samples – Better Decisions – Faster
On Demand
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Optimizing SEC for Analysis of Antibodies and Antibody–Drug Conjugates
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If you would like to submit an article to LCGC, contact Laura Bush, Editorial Director - laura.bush@ubm.com
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