LCGC Europe Application Note Alert Having trouble viewing this email? Click here Method Development for Impurity Analysis Using 2D-LC This application shows how multiple heart-cutting 2D-LC helps uncover coelution during method development for impurity analysis of fine chemicals or pharmaceuticals. Automated Desalting for MS Analysis Using 2D-LC This application shows how multiple heart-cutting 2D-LC is used for automated desalting prior to mass selective detection. Glucagon is analyzed according to USP 39. Benefits of 2D-LC–MS/MS in Pharmaceutical Bioanalytics The application shows the analysis of cell supernatants from an in vitro suspension-based assay. The power of 2D-LC–MS/MS separated 16 target metabolites in 35 min. Online 2D-LC Characterization of Monoclonal Antibodies This application shows how 2D-LC combines SEC and WCX to achieve excellent resolution and precision in both dimensions for characterization of mAbs in a 13-min run. Direct 2D-LC Analysis of Oligonucleotides This application shows how 2D-LC eliminates manual desalting and sample preparation to achieve a threefold increase in workflow speed for analysis of oligonucleotides. 2D-LC for Pharmaceutical Impurity Analysis This application shows how high-resolution sampling 2D-LC separated two closely eluting compounds where the low-concentration impurity was concealed by the API peak.