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The Column
December 20, 2018
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Characterizing Protein-Nucleic Acid Conjugates with Light Scattering

This article presents two case studies regarding the characterization of protein-DNA complexes using two complementary multi-angle light scattering (MALS) techniques. read more


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Exclusive Interview from ASMS 2018

Transform Small Molecule Characterization and Identification in Drug Development.
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The Role of Mass Spectrometry in Biopharmaceutical Drug Discovery and Development

The discovery and development of biopharmaceuticals that target specific diseases can be transformative for people living with illness. However, bringing a new therapy to market is a prolonged and costly process mired in uncertainty. Ensuring safety, efficacy, and product quality is paramount.read more


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Analysis of Next-Generation Protein Biopharmaceuticals

Tips for effective use of chromatography and mass spectrometry (MS) for the analysis of antibody–drug conjugates, glycoengineered proteins, and biosimilars. read more

Rum Classification Using HS-SPME-GC–MS

Researchers from the University of Almeria have developed a method for the classification of rum using HS-SPME-GC–MS. read more

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Application Note

µPAC™ column performance with peptide standards: Thermo Scientific™ Pierce™ retention time calibration mixture.

The outstanding reproducibility of PharmaFluidics' µPAC™ column for bottom-up proteomics experiments is demonstrated with an internal retention time standard.
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Practical Ultrahigh-Performance Liquid Chromatography (UHPLC)

Increasing efficiency and resolution whilst reducing costs have driven the uptake of UHPLC. We outline how technologies evolve to give new options to chromatographers.
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