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The Column

May 21, 2020
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Top Story

The Benefits of Using a Method Life Cycle Approach to Improve Method Quality

The Column spoke to Evelien Dejaegere from Waters Corporation about the method life cycle management approach and its importance in the pharmaceutical sector. Read more


Features

Tips & Tricks GPC/SEC: Aqueous GPC/SEC for Water-Soluble Macromolecules

Water-soluble macromolecules require water as a mobile phase, and method development therefore seems to be straightforward. At second glance, however, aqueous gel permeation chromatography/size-exclusion chromatography (GPC/SEC) is complex and the choice of the stationary phase and pH are crucial. In addition, mobile phase additives are often required to allow for interaction-free separations. Read more


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Highlights of SFC 2019

A review of the 13th International Symposium on Packed Column SFC and SFE Techniques (SFC 2019), which was held in Philadelphia, Pennsylvania, USA, on 29 September–1 October 2019. Read more


Nitrosamine Determination Using GC–PCI-QTOF-MS

Researchers have developed an alternative method to reduce interferences for the analysis of N-nitrosamines using GC coupled to HR-QTOF-MS. Read more

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