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The Column
May 17, 2018
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TOP STORY

Three Peak Shapes You Really Don't Want to See in Your Gas Chromatogram

Sometimes troubleshooting a separation can rely upon the end user spotting subtle clues within the chromatogram, and at other times the visual signs can be much more obvious. read more


Features

Tips & Tricks: GPC/SEC: How Do Calibration Curves Influence GPC/SEC Results?

How the type of calibrants and the quality of the calibration curve influences the results is discussed in this instalment of Tips & Tricks. read more

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Impact Support Mats Protect Microplates During Centrifugation

Silicone impact support mats from Porvair Sciences are designed to protect deep well microplates when they are being centrifuged. Fitting snugly into the skirt of the deep well plates, silicone impact support mats allow plates to be used in a centrifuge without risking plate distortion, cracking or breaking, resulting in well leakage and loss of valuable samples. Impact support mats are now available for Porvair Sciences square deep well plates (2ml, 1ml and 350ul), round well plates (2ml & 1ml) and range of large volume deep well plates. Learn more

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Backpressure regulation up to 300bar

As an extension to the VICI Jour® Back Pressure Regulators the new JR-BPR3 offers an extended application range. Pressures from 90-300bar (1300-4200psi) are easily manual adjustable. The body is made of stainless steel and the inert membran bar enables the usage of any HPLC mobile phase and of supercritical CO2. The JR-BPR3 can also be mounted into any column oven up to 80°C. Learn more

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FEATURES

The Role of Chiral Chromatography in Antiepileptic Drug Development and Epilepsy Therapy

The Column spoke to Arcadius V. Krivoshein, Assistant Professor of Chemistry at the University of Houston–Clear Lake, USA, about his work developing 3-ethyl-3-phenylpyrrolidin-2-one (EPP), an experimental anticonvulsant that can help to stop convulsions during epileptic seizures, and the role of chiral high performance liquid chromatography (HPLC) in this research. read more

News

Investigating the Role of Amino Acids in Celiac Disease Development

Researchers from the University of Gothenburg, in Gothenburg, Sweden, have investigated whether plasma amino acid levels differed among children with celiac disease using LC–MS. read more


Featured Products

NEW Sample automation & concentration platform

Centri® – a multi-technique sample automation, pre-concentration and injection platform for GC that delivers enhanced analytical sensitivity and higher throughput for VOC and SVOC analysis in liquid, solid and gas samples. / Learn more /

New YMC HIC column

YMC's BioPro HIC BF is a new high-resolution column phase designed for the HPLC analysis of antibodies, antibody-drug conjugates (ADCs) and proteins by hydrophobic interaction chromatography. The butyl bonded polymer phase provides long-term stability and ensures excellent lot-to-lot reproducibility. BioPro HIC BF improves analysis throughput with virtually no carryover effects. / Learn more /

Ultrafast Speed and Resolution

Daicel's META immobilised column screening set available in sub-2 micron particle size.
The CHIRALPAK® IA-U, IB-U, IC-U & IG-U screening set offers:
• ULTRAFAST SEPARATIONS
• HIGHER RESOLUTION POWER
• SOLUTIONS IN SECONDS
/ Learn more /


Application Notes

µPAC™ column robustness in bottom-up proteomics

The separation bed of the µPAC™column consists of an array of freestanding silicon pillars with 2.5 µm spacing in between them, contributing to:

  • an unrivalled robustness and longevity of the column
  • an excellent resilience towards “challenging” proteomics samples
  • 4 times less likely to clog in comparison to traditional columns
/ Learn more /

Application Compendium - GPC/SEC Polymer Analysis

  • Identify polymer key physical parameters and molecular weight distribution
  • Analyze tough polymers with a high-performance, integrated GPC system
  • Characterize polymers to optimize their engineering and performance
/ Learn more /

Highly Accurate Transfer of Liquids

  • Highly accurate liquid dispensing for improved quality of analysis results
  • Amounts can be verified using an integrated balance with traceable log
  • Useful for dilution series, generating/adding standards, sample introduction
Read more


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