Electrochemical simulation of phase I metabolism of three novel cardiovascular drugs and comparison with in vivo data (human urine) reveals the power of EC-MS.
Electrochemical oxidation for fast mimicking of phase I metabolism of Triclosan and its transformation products including their synthesis for toxicological evaluation.
Rapid and cost-effective synthesis of milligram quantities of metabolites or reference materials for structural identification by MS, NMR, or for toxicology studies.