LCGC Europe Application Note Alert
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LCGC Europe
SEC
Quantifying CQAs of Gene Therapy Vectors
SEC–MALS–UV-RI analysis quantifies multiple critical quality attributes of AAV viral vectors, including concentration/titer, aggregation, and empty:full ratio.
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GC
Hydrocarbon Analysis with Agilent 8890 GC
Analysis of monocyclic aromatic hydrocarbons in accordance with ASTM method D7504 with the Agilent 8890 GC and DB-Heaver Wax columns.
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N-Nitrosamines in Rubber Teats, Soothers, and Toys
This note looks at the analysis of N-nitrosamines in rubber teats, soothers, and toys, with specific focus on babies and young children under UK method BS EN 71-12:2016.
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GC–MS
Automated Aroma Profiling of Wine
Headspace sorptive extraction with GC×GC–TOF-MS/SCD provides comprehensive information on wine aroma and odour on a single, fully-automated, cryogen-free platform.
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The Chemistry of Pumpkin Spice
Pumpkin spice is one of Autumn’s favourite flavours. In this application note we look at the chemistry of the flavours of pumpkin spice.
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Sample Prep
Mycotoxins: Fully Automated Edible Oil Analysis
Automated liquid extraction, clean-up and LC-MS/MS determination of mycotoxins in edible oil, including accurate transfer of oil samples, is presented and data reported
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Glyphosate Analysis in Wine Using SPE
See a simple and fast SPE method for the LC–MS/MS analysis of glyphosate, AMPA, and glufosinate in red wine without derivatization using AFFINIMIP® SPE Glyphosate.
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HILIC Separation of Lipid Classes Using iSPE®-HILIC
An efficient separation of polar and nonpolar lipid representatives was achieved utilizing iSPE®-HILIC material. The lipids were separated according to their polarity.
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LC
Multi-Attribute Analysis of Monoclonal Antibodies
Multi-attribute analysis combines protein A affinity chromatography, SEC, and LC/MS in a 3D setup for assessment of features including mAb titer and size variants.
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mAb Method Using Isopropanol in HIC
This application note shows how to achieve higher recoveries for commercially available mAbs using 15% isopropanol as modifier in HIC mode.
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LC-MS
New Tools for Proteomics
With Antec Scientific’s new µ-PrepCell-SS, electrochemical reduction of disulfide bonds in proteins, mAbs, and other biopharmaceuticals is possible in any LC-MS workflow.
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Integrating the Analysis of Ultrashort-Chain PFAS
Method development for simultaneous analysis of ultrashort-chain, alternative, and legacy PFAS
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