LCGC Europe Application Note Alert
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LCGC Europe
Sample Prep
Comprehensive Screen of Acidic/Neutral/Basic Drugs from Blood and Urine
This note exploits the highly retentive, universal nature of UCT’s polymeric Styre Screen® HLD sorbent for the analysis of acidic, neutral, and basic compounds.
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Enrichment of Glycopeptides Using iSPE®-HILIC Material
An effective enrichment method for glycopeptides were developed based on iSPE®-HILIC material. It opens a range of opportunities for glycoproteomics research.
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LC
Automated LC Method Development and Robustness Tests
This technical overview demonstrates automated method development of pharmaceutical samples using the Agilent 1290 Infinity II LC combined with ChromSwordAuto software.
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Overcoming Separation Challenges in Biological Drug Development
Learn how to improve your LC separations at all stages in the biological drug development process, including ways to develop deeper understanding of the drug product.
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LC–MS
FDA Method for Determination of NDMA in Ranitidine
FDA recently posted an LC–HRMS method using the novel ACE 3 C18-AR column, which can be used by regulators to detect “probable human carcinogen” NDMA in ranitidine.
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GC
Hydrocarbon Analysis with Agilent 8890 GC
Analysis of monocyclic aromatic hydrocarbons in accordance with ASTM method D7504 with the Agilent 8890 GC and DB-Heaver Wax columns.
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GC–MS
Aroma Profiling of Hops and Beer
Using a single-platform, multi-hyphenated analytical system to detect odour taints and to provide flexible yet comprehensive aroma profiling of hops and beer.
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SFC
Determination of Pyrrolizidine Alkaloids in Tea Using SFC–MS/MS
An SFC–MS/MS method for high sensitivity analysis of 34 PAs in commercial tea samples was developed.
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Chiral Chromatography
SFC Achiral Separation Utilizing a Chiral Column
This application note demonstrates the ability of Daicel’s CHIRALPAK® IA-3 to perform both chiral and achiral separations using SFC and hydrobenzoin as a test compound.
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