In our December issue:
COLUMNS:
LC TROUBLESHOOTING
Effect of Flow Rate on UV Detection in Liquid Chromatography
If I increase the flow rate of my separation when using UV absorbance detection, should I expect peak area to change?
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QUESTIONS OF QUALITY
Can We Continue to Draw the Line?
Chromatographic peak integration continues to be a major regulatory issue and was first discussed in this column in 2015. Is the approach to manual intervention and manual integration outlined still acceptable in the light of regulatory citations and guidance documents published since then? Read more >>
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| FEATURES: |
Analysis Focus: Forensic Analysis Exploring Energetic Materials Using Nontargeted Analysis
LCGC Europe spoke to Leon Barron and Matteo Gallidabino to discuss novel nontargeted approaches to analyze explosive materials using ion chromatography (IC) with high resolution mass spectrometry (HRMS), and the challenges and solutions analysts can encounter when developing nontargeted methods.
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| PEER-REVIEWED ARTICLE: |
Ion Chromatography for Small Molecule Determination in Clinical and Pharmaceutical Analysis
This article presents possible uses of IC and related techniques combined with various detection methods for clinical and pharmaceutical analysis of common inorganic and organic anions and cations. An overview of achievements in this area from the past 10 years is presented and the most important trends and development perspectives for IC are described.
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| UPCOMING WEBCASTS |
The CHROMacademy Essential Guide Webcast: Understanding GC Sample Introduction
Thursday 12th Dec. 2019, 11:00am EST | 8:00am PST | 4:00pm GMT | 5:00pm CET
Register » |
Editors' Series: Streamlined Characterization of Antibody-Drug Conjugates by Two-Dimensional (2D) and Four Dimensional (4D) LC-MS
Thursday, December 12, 2019 at 11am EST | 8am PST | 4pm GMT | 5pm CET
Register » |
Capillary Flow LC-MS Using Micro Pillar Array Columns: Combining Nano Flow Sensitivity with Analytical Flow Robustness and Throughput
Friday, Dec. 13, 2019 at 10am EST | 9am CST | 3pm GMT | 4pm CET
Register » |
