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In our November issue:
COLUMNS:
LC TROUBLESHOOTING
Column Re-Equilibration
Questions about how long liquid chromatography (LC) columns should be re-equilibrated following solvent gradient elution separations are commonly raised and discussed by LC users. In this article we discuss the details in light of recent research on this topic, and show that satisfactory results can be obtained with short re-equilibration periods on the order of two column volumes, even for hydrophilic interaction chromatography (HILIC) separations.
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GC CONNECTIONS
Advances in Online LC–GC
In this instalment of “GC Connections”, the advantages of multidimensional chromatography with HPLC as the first dimension and GC as the second are discussed. Read more >>
THE ESSENTIALS
The Top Three HPLC Method Development Tips
These three important tips provide a clear starting point for the development of any HPLC method, to achieve optimum resolution in the minimum amount of time. These tips make it possible to obtain the best data while reducing running costs and analysis time.
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FEATURES:
SEC in Nanoparticle Analysis
In the second part of this interview on size-exclusion chromatography (SEC) André Striegel discusses the benefits of the technique to analyze nanoparticles and quantum dots, the complementary role of hydrodynamic chromatography (HDC), and the future of SEC in two-dimensional liquid chromatography (2D-LC) separations.

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PEER-REVIEWED ARTICLE:
Screening for Chemicals in Plastic Food Packaging
The occurrence of additives, such as plasticizers in plastic food packaging, has been documented, but information on their potential migration into foods is limited. In this pilot study, 2D GC–MS was used to identify chemicals extracted from a common stretch plastic film with a series of organic solvents.

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UPCOMING WEBCASTS
Thermal Desorption-Direct MS: A Breakthrough in Analysis Speed and Throughput
Wednesday, Nov. 20, 2019 at 11am EST | 8am PST | 4pm GMT | 5pm CET

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Editors’ Series: Strategies for Improved Pharmaceutical Sample Preparation
Thursday, Nov. 21, 2019 at 10am EST | 9am CST | 3pm GMT | 4pm CET

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In a Pickle with Pesticides Sample Prep? Achieve Higher Recoveries with Rapid, Automated Extraction of Any Food Matrix
Friday, Nov. 22, 2019 at 11am EST | 8am PST | 4pm GMT | 5pm CET

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