FEATURES
Ultrahigh-pressure size-exclusion chromatography (UHP-SEC) offers multiple benefits for synthetic polymer characterization. However, despite the many advantages of UHP-SEC, its rapid, low-volume separation is more sensitive to column calibration errors and drift than traditional high performance (HP)-SEC. Additionally, only a small selection of column chemistries are available. It is therefore essential to combine UHP-SEC with online, low-volume multi-angle light scattering instrumentation (UHP-SEC-MALS) to overcome these challenges. Read more
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Introducing the next generation DAWN multi-angle static light scattering (MALS) detector for absolute characterization of the molar mass and size of macromolecules and nanoparticles in solution. DAWN offers high sensitivity, a wide range of molecular weight, size, and concentration, and a large selection of configurations and optional modules for enhanced capabilities.
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The functional properties of polymers, such as poly(lactic-co-glycolic acid) (PLGA), relevant to drug delivery and biomedical devices, are governed by the molecular properties of molar mass, composition, conformation, and branching. This article demonstrates how such polymers are fully characterized, quickly and absolutely, using gel permeation chromatography (GPC) with multi-angle light scattering (MALS) and online viscometry. Read more
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