Live Webcast Europe: Thursday, October 10, 2019 at 2pm BST | 3pm CEST North America: Thursday, October 10, 2019 at 2pm EDT | 1pm CDT | 11am PDT Event Overview Process impurities such as host cell proteins (HCPs) can threaten product efficacy and stability and, therefore, must be monitored and controlled in drug products. The traditional enzyme-linked immunosorbent assay (ELISA) method lacks the specificity and coverage to identify and quantify individual HCPs. Liquid chromatography (LC)–mass spectrometry (MS) analysis overcomes these limitations; however, the coelution of low-abundance HCP peptides with the highly abundant peptides from the drug product demands better separation of the peptides and broad dynamic range of the LC/MS system. In this webcast, experts will review an HCP analysis workflow for automated sample preparation; an LC–MS/MS analysis using a new acquisition method shown to improve protein identification; and data analysis software to confirm identification of HCPs. Key Learning Objectives How to optimize each stage of a host cell protein workflow including sample prep, separation, detection, and data processing How a new acquisition method can identify lower-level peptides How to perform targeted quantitation of HCPs For Research Use Only. Not for use in diagnostic procedures. Presenters Steve Madden Software Product Manager Agilent Technologies Linfeng Wu, PhD Application Scientist Agilent Technologies Moderator Alissa Marrapodi Custom Content Editor LCGC Register now Sponsored by: Unable to attend? All registrants receive a link to a recorded version of the webcast.