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Demystify HCPs with Cygnus
advanced orthogonal methods!
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How can you better identify those host cell proteins (HCPs) that might co-purify with your drug substance (DS) and elicit an undesired immune response, interfere with drug safety and efficacy, or impact DS stability? Incorporate powerful orthogonal methods into your analysis with
Antibody Affinity Extraction (AAE™) and AAE-Mass Spectrometry (AAE-MS) Services to:
Enrich hitchhiker HCPs to detectable levels and improve MS resolution Optimize your purification process to remove problematic HCPs Assure that your HCP ELISA is fit for purpose of process monitoring and product lot release Provide comprehensive HCP characterization data to regulatory agencies
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