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LCGC TV: Luigi Mondello on the Fundamentals of 2D LC
Comprehensive liquid chromatography (LC) is a multidimensional technique that has the potential to increase peak capacity resolution when separating complex mixtures, especially in food analysis. In this new video from LCGC TV, Luigi Mondello from the University of Messina, Italy, describes the fundamental principles of 2D LC, and explains the advantages over 1D LC. |
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| Peptides and Proteins are not Small Molecules; Why Treat Them the Same? |
Large molecule quantification is one of the greatest challenges that bioanalysts face. Sensitivity and specificity issues are numerous: fewer molecules per volume; increased fragmentation; limited recovery due to complex sample prep; and so on.
 Download Peptide and Protein Bioanalysis Application Notebook and infographic. Learn why Waters is leading the industry in large molecule bioanalysis.
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| The LCGC Blog |
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HPLC Column Transfer from Fully Porous to Core-Shell Particles in Three Simple Equations
LCGC Blogger Tony Taylor says that when “messing about” with HPLC methods and changing column dimensions and particle morphologies (from fully porous to core-shell type columns, for example), if one does not change the gradient steepness, then there may be significant changes not only to retention times but also to the selectivity (and resolution) between peaks within the chromatogram. |
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| Shift to the power of OpenLAB CDS. |
Combining advanced functionality with intuitive software control, OpenLAB CDS enables you to work faster, gain productivity, and get the most from your instruments. To learn more about Agilent’s latest OpenLAB Chromatography Data System (CDS), visit  Agilent OpenLAB CDS.
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| There's only one Millex® filter |
Restek's EZGC® Online Suite |
The most versatile HPLC column on the market. Efficient, reproducible peaks in Reverse Phase, Normal Phase or Aqueous Normal Phase. Can separate polar and non-polar compounds in the same run.  Learn more |
Speed Up Method Development With Restek's EZGC® Suite. These tools will save you hours of calculations and guesswork. Free, web-based applications help you create model chromatograms, get column recommendations, translate methods and calculate flows!  Learn more |
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