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19 June 2014
In this Issue
What Forensic Labs are Up Against
Analysts in forensic labs work in a challenging landscape, where the targets of analysis keep changing. In two new short video clips, Tom Brettell explains how these challenges play out in terms of their use of GC columns and GC methods. More...
Simplified, multi-phosphorylated peptide or glycan isolation
New ERLIC-WAX chemistry from The Nest Group, Inc., in both column and microSPE formats, addresses multi-phosphorylated peptide and glycan isolation challenges. Desalting with TARGA® C18, UltraMicroSpin™ SPE from 100% water can improve recovery of these polar molecules prior to LCMS. Try one of our ERLIC WAX & TARGA separation approaches today! The Nest Group, Inc. - "Not Just Columns ... Answers!"
Profiling MDMA Impurities Using HS–SPME
Profiling impurities in MDMA (also known as ecstasy) is essential to forensic science as different profiles can provide clues about the source. Two researchers from Michigan State University (Michigan, USA) investigated the effect of liquid–liquid extraction (LLE), headspace solid-phase microextraction (HS–SPME), and different gas chromatography temperature programmes highlighting the need for standardized procedures. More...
Solutions to Your Challenges in Ion Chromatography
We all know that chromatography is full of complexity. The Chromatography Solution Center is here to help. The Solution Center, developed by LCGC in coordination with Thermo Scientific, can help you find answers to your analytical challenges by providing a variety of articles, application notes, videos, and other resources - updated monthly. Check out this month's installment of the Ion Chromatography section
Are All HPLC C18 Phases the Same?
It’s just a silica support with a C18 bonded on – surely there can’t be much difference between them? Wrong. There are huge differences between standard C18 phases and simply swapping one C18 for another, without accounting for these differences, will produce differences in retention time, resolution, and peak elution order. More...
Current features
Simultaneous Determination of Methylxanthines and Cotinine in Human Plasma by Solid-Phase Extraction Followed by LC–MS–MS
A multi-residue method has been developed and validated for the analysis of methylxanthines (caffeine and its metabolites) and cotinine in human plasma. The method has been successfully applied to the analysis of 500 samples from pregnant women in a clinical study. More...
3D Printing — A Chromatographic Revolution?
Incognito speculates on how 3D printing could change life in the laboratory. More...
Featured Product
So Smart it almost runs itself!
Improving precision and throughput, Shimadzu’s new GCMS-TQ8040 is the most accurate, cost effective, easy-to-use triple quadrupole GCMS ever. The system combines Ultra-Fast Mass Spectrometry (UFMS) and Smart Multiple Reaction Monitoring (MRM) based on Shimadzu's patented UFsweeper™ technology. Learn more
On Demand Webcasts
The Analysis of Dioxins in Food with a High Performance GC-Triple Quadrupole System Accoding to EU 252/2012 Regulations
Making Better GC Connections While Ensuring an Inert Sample Flow Path
Complete Inorganic Elemental Speciation Analysis Solutions for Food Safety
Editors’ Series: Analysis and Identification of Emerging Contaminants and their Transformation Products in River Water, Urban Water, and Hospital Wastewaters: Sample Preparation and LC–MS Techniques
Features of Different Mass Analysers Applied to Multi-Allergen Screening
Monoclonal antibodies complete primary structure and biosimilarity assessment in a single analysis using CESI–MS–MS
Need GC Troubleshooting Help?

CHROMacademy announces the launch of the interactive GC Troubleshooter, sponsored by Thermo Scientific.
Building on the success of our ground breaking HPLC Troubleshooter, we are excited to announce the GC version.  In 3 simple steps you will overcome your instrument, separation and quantitation issues.  It’s completely free - so if you haven't tried our troubleshooter before you're in for a surprise! Click Here
The Column
The Global E-zine for Separation Scientists
The global edition of The Column is delivered twice monthly with a screen-optimized format designed to improve readability. Covering topical issues, application-based articles, market reports, tips and tricks, opinion pieces and interviews, The Column is a great information resource helping readers achieve better day-to-day working practices.
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Upcoming Webcasts
LC Troubleshooting 3.0 – The Smart Art of LC Troubleshooting Automation
Tuesday 1 July 2014 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST
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Qualitative and Quantitative Analysis of Protein Modifications Using CESI–MS and nanoLC–MS
Tuesday 8 July 2014 8:00 AM PDT/ 10:00 AM CDT/ 11:00 AM EDT
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Polymer Characterization Using Multi-Detector Ambient and High Temperature Gel Permeation Chromatography
Wednesday 23 July 2014 11:00 AM PDT/ 2:00 PM EDT
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