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18 December 2014
In this Issue
The LCGC Blog:  Intact Protein Separations: Some Education is Missing
Small-molecule chromatographic theory can be quite straightforward, but analysis of proteins requires a much wider breadth of knowledge and understanding of appropriate techniques and approaches. Further, manufacturers continue to innovate and provide new separation materials; these will have different performance properties than materials reported on a decade or more ago. More...
Need HPLC Troubleshooting Help?
The CHROMacademy interactive HPLC Troubleshooter, sponsored by Thermo Scientific, was designed with busy chromatographers in mind. In 3 simple steps ChromAcademy can help you overcome your instrument, separation and quantitation issues. It’s completely free — so if you haven't tried our troubleshooter before you're in for a surprise! Learn more
LCGC TV: Improving ROI in the Laboratory
Analytical laboratories need to shift from simply thinking about reducing costs to thinking about return on investment. In this new video, Merlin Bicking, President and Senior Analytical Scientist from ACCTA discusses examples of how costs can be cut without just reducing expenses. More...
HPLC for Characterization and Quality Control of Therapeutic Monoclonal Antibodies
Monoclonal antibodies (mAbs) are highly complex recombinant proteins successfully used as therapeutics in many disease indications. This instalment describes recent advances and best practices in HPLC analysis of intact mAbs and their variants and fragments. More...
Chinese American Chromatography Association Provides Networking, Career Support, and a Sense of Community
Over the last 20–30 years, the number of Chinese separation scientists has grown enormously both at universities and in the workplace, prompting interest in networking events and regular gatherings. In 2008, the not-for-profit Chinese American Chromatography Association (CACA) was formed. More...
Avoiding LC–MS Signal Suppression
Some practical insights into optimizing LC–MS eluents and parameters to avoid signal suppression. The following “Ask the Expert” question regarding the suppression of MS signals got the CHROMacademy team thinking... More...
Need LC Troubleshooting Help?

CHROMacademy has developed the HPLC Troubleshooter with busy chromatographers in mind. Sponsored by Thermo Scientific, in 3 simple steps you will overcome your instrument, separation and quantitation issues.  It’s completely free - so if you haven't tried our troubleshooter before you're in for a surprise! Click Here
The Column
The Global E-zine for Separation Scientists
The global edition of The Column is delivered twice monthly with a screen-optimized format designed to improve readability. Covering topical issues, application-based articles, market reports, tips and tricks, opinion pieces and interviews, The Column is a great information resource helping readers achieve better day-to-day working practices.
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Upcoming Webcasts
Editors’ Series: Multiclass, Multiresidue Monitoring of Veterinary Drug Residues in Food Animal Tissues
Wednesday 3 December 2014 8 am PST/ 11:00 am EST
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Streamline Data Analysis of Tandem Mass Spectrometry for Inborn Errors of Metabolism Research
Wednesday 10 December 2014 8:00 am PST/ 11:00 am EST/ 4:00 pm GMT/ 5:00 pm CET
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Fast and Accurate Analysis of Beer and Wort Samples Using Automated Discrete Analysis
Thursday 11 December 2014 8:00 am PST/ 11:00 am EST/ 4:00 pm GMT/ 5:00 pm CET
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