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29 May 2014
In this Issue
Common Errors in the Laboratory
We all make mistakes. The first step to correcting them is recognizing them, and learning the right way to do things. In two new short videos, Merlin Bicking talks about two common errors that chromatographers make, and how to avoid them. More...
Thermo GC/MS eBook
LCGC E-Book: Advances in GC-MS Analysis of Pesticides
In this new e-book, authors from the US Department of Agriculture, academia, and a European Union Reference Laboratory discuss advances in the analysis of pesticide residues using gas chromatography–mass spectrometry (GC–MS) methods. Download PDF to Download on iTunes
Guo-Fang Pang Wins AOAC International's 2014 Harvey W. Wiley Award
AOAC International (Gaithersburg, Maryland, USA) has named Guo-Fang Pang as the recipient of the 2014 Harvey W. Wiley Award in recognition of his outstanding contributions to analytical chemistry. Pang will accept the award—AOAC’s highest scientific honour—at the opening session of the 128th AOAC International Annual Meeting & Exposition in Boca Raton, Florida, USA, 7–10 September 2014. More...
GC–MS Detects and Identifies Four Ozone Depleting Gases in Atmosphere
Four new ozone-depleting substances (ODSs) — CFC-1121, CFC-112a, CFC-113a, and HCF-133a — have been detected and identified in the Earth’s atmosphere using gas chromatography–mass spectrometry (GC–MS).1 The research published in Nature Geoscience compared samples collected between 1978 and 2012 to establish a clear increase in the emissions of these gases, even though CFC production has been banned globally since 1987. More...
Current features
The Essentials: Mixed-Mode HPLC Separations: What, Why, and How
In this excerpt from LCGC’s e-learning tutorial, the mechanisms of mixed-mode chromatography are explained, with reference to the parameters that are used to optimize selectivity and retention. More...
UHPLC Method Development and Modelling in the Framework of Quality by Design
The goals in ultrahigh-pressure liquid chromatography (UHPLC) method development are to first find the best separation, second find the best column, and third find the most robust method in a multifactorial Design Space. Trial and error methods are not sufficient anymore and solid science based on Quality by Design (QbD) principles is required. Control strategies and continual improvements of the methods are necessary, which offer much greater flexibility in the quality control laboratories than before. Modelling tools based on QbD principles used in method development give transparency to the control of multivariable influences and achieve faster drug applications and commercial authorization by the regulatory agencies. More...
Application Notes
Markes International
Enhancing Aroma Profiling of Wine with GC–TOF–MS
Nick Bukowski, Laura McGregor, and Steve Smith
This application note demonstrates that BenchTOF time-of-flight mass spectrometers coupled with GC can provide a high-performance solution for the detection and quantitation of aromatic compounds in wine extracts. In particular, we show how the ChromCompare software Smodule allows rapid identification of differences between samples, and how Select-eV variable-energy ionization capability enhances both the sensitivity and selectivity of analyses. Learn more

Multimedia
Increasing Laboratory Efficiency through a Harmonized Compliance Solution
HPLC for Pharmaceutical Analyses: Succeed with Sample Filtration and Optimized Water Quality
High Resolution MS Screening and Quantitation Method for Contaminants in Dietary Supplements
Need GC Troubleshooting Help?

CHROMacademy announces the launch of the interactive GC Troubleshooter, sponsored by Thermo Scientific.
Building on the success of our ground breaking HPLC Troubleshooter, we are excited to announce the GC version.  In 3 simple steps you will overcome your instrument, separation and quantitation issues.  It’s completely free - so if you haven't tried our troubleshooter before you're in for a surprise! Click Here
The Column
The Global E-zine for Separation Scientists
The global edition of The Column is delivered twice monthly with a screen-optimized format designed to improve readability. Covering topical issues, application-based articles, market reports, tips and tricks, opinion pieces and interviews, The Column is a great information resource helping readers achieve better day-to-day working practices.
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